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    PAP2 Purple acid phosphatases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837949, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAP2
    Official Full Name
    Purple acid phosphatases superfamily protein
    Primary source
    TAIR:AT1G13900
    Locus tag
    AT1G13900
    See related
    Araport:AT1G13900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16A14.11; F16A14_11; purple acid phosphatase 2
    Summary
    Encodes a dual-localized acid phosphatase (mitochondria and chloroplast) that modulates carbon metabolism.
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    Genomic context

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    See PAP2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (4753099..4755656, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ELM2 domain-containing protein Neighboring gene soluble N-ethylmaleimide-sensitive factor adaptor protein 30 Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene Remorin family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtPAP2 is a tail-anchored protein in the outer membrane of chloroplasts and mitochondria. Sun F, et al. Plant Signal Behav, 2012 Aug. PMID 22751362, Free PMC Article
    2. A dual-targeted purple acid phosphatase in Arabidopsis thaliana moderates carbon metabolism and its overexpression leads to faster plant growth and higher seed yield. Sun F, et al. New Phytol, 2012 Apr. PMID 22269069
    3. Phosphorylation and Dephosphorylation of the Presequence of Precursor MULTIPLE ORGANELLAR RNA EDITING FACTOR3 during Import into Mitochondria from Arabidopsis. Law YS, et al. Plant Physiol, 2015 Oct. PMID 26304849, Free PMC Article
    4. RNA editing of cytochrome c maturation transcripts is responsive to the energy status of leaf cells in Arabidopsis thaliana. Sun Y, et al. Mitochondrion, 2017 Jul. PMID 28478183
    5. Label-free protein quantification for plant Golgi protein localization and abundance. Nikolovski N, et al. Plant Physiol, 2014 Oct. PMID 25122472, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtPAP2 is the first purple acid phosphatase shown to modulate carbon metabolism and the first shown to be dual-targeted to both plastids and mitochondria by a C-terminal targeting signal.[AtPAP2]
      Title: A dual-targeted purple acid phosphatase in Arabidopsis thaliana moderates carbon metabolism and its overexpression leads to faster plant growth and higher seed yield.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_101256.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables acid phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables mitochondrion targeting sequence binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein insertion into mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of carbohydrate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with chloroplast IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endosome HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in intracellular anatomical structure IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with mitochondrion IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    Purple acid phosphatases superfamily protein
    NP_172843.1
    • Purple acid phosphatases superfamily protein; FUNCTIONS IN: hydrolase activity, protein serine/threonine phosphatase activity, metal ion binding, acid phosphatase activity; INVOLVED IN: biological_process unknown; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Purple acid phosphatase, N-terminal (InterPro:IPR015914), Metallophosphoesterase (InterPro:IPR004843), Purple acid phosphatase-like, N-terminal (InterPro:IPR008963); BEST Arabidopsis thaliana protein match is: purple acid phosphatase 9 (TAIR:AT2G03450.1); Has 1738 Blast hits to 1720 proteins in 355 species: Archae - 1; Bacteria - 507; Metazoa - 197; Fungi - 77; Plants - 727; Viruses - 0; Other Eukaryotes - 229 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4753099..4755656 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101256.3 → NP_172843.1  Purple acid phosphatases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172843.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5MAU7, Q9LMG7
      UniProtKB/TrEMBL
      A0A178WAN1, A0A5S9UBX3, A0A7G2DVK0
      Conserved Domains (3) summary
      cd00839
      Location:254 → 577
      MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
      pfam17808
      Location:26 → 105
      fn3_PAP; Fn3-like domain from Purple Acid Phosphatase
      pfam16656
      Location:145 → 245
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LMG7.1

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