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    PUM4 pumilio 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820198, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUM4
    Official Full Name
    pumilio 4
    Primary source
    TAIR:AT3G10360
    Locus tag
    AT3G10360
    See related
    Araport:AT3G10360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    APUM4; pumilio 4
    Summary
    Encodes a member of the Arabidopsis Pumilio (APUM) proteins containing PUF domain (eight repeats of approximately 36 amino acids each). PUF proteins regulate both mRNA stability and translation through sequence-specific binding to the 3' UTR of target mRNA transcripts.
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    Genomic context

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    See PUM4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Sequence:
    Chromosome: 3; NC_003074.8 (3210884..3215621, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Cyclin-like family protein Neighboring gene phenylalanine ammonia-lyase 4 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene FAD-dependent oxidoreductase family protein Neighboring gene subunit of exocyst complex 8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of Arabidopsis thaliana PUF proteins--binding specificity and target candidates. Francischini CW, et al. FEBS J, 2009 Oct. PMID 19682068
    2. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    3. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    4. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111871.7

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    pumilio 4
    NP_187647.2
    • pumilio 4 (PUM4); FUNCTIONS IN: RNA binding, binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: male gametophyte, cultured cell, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Pumilio RNA-binding repeat (InterPro:IPR001313), Nucleic acid binding NABP (InterPro:IPR012940), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: pumilio 1 (TAIR:AT2G29200.1); Has 3756 Blast hits to 2007 proteins in 241 species: Archae - 0; Bacteria - 4; Metazoa - 783; Fungi - 1274; Plants - 892; Viruses - 0; Other Eukaryotes - 803 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3210884..3215621 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111871.7 → NP_187647.2  pumilio 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187647.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GY24, Q9SS47
      UniProtKB/TrEMBL
      A0A178VKI4, A0A5S9XBD8, A0A7G2EMU4
      Conserved Domains (2) summary
      cd07920
      Location:659 → 980
      Pumilio; Pumilio-family RNA binding domain
      pfam07990
      Location:313 → 663
      NABP; Nucleic acid binding protein NABP
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SS47.2

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