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    3-phosphoinositide-dependent protein kinase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820219, updated on 18-Sep-2024

    Summary

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    Official Full Name
    3-phosphoinositide-dependent protein kinase
    Primary source
    TAIR:AT3G10540
    Locus tag
    AT3G10540
    See related
    Araport:AT3G10540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    11
    Sequence:
    Chromosome: 3; NC_003074.8 (3289677..3292909)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene LOSS OF GIANT CELLS FROM ORGANS Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene Myotubularin-like phosphatases II superfamily Neighboring gene Cytochrome P450 superfamily protein Neighboring gene cytochrome P450, family 77, subfamily A, polypeptide 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A protein kinase target of a PDK1 signalling pathway is involved in root hair growth in Arabidopsis. Anthony RG, et al. EMBO J, 2004 Feb 11. PMID 14749726, Free PMC Article
    2. Members of the Plant CRK Superfamily Are Capable of Trans- and Autophosphorylation of Tyrosine Residues. Nemoto K, et al. J Biol Chem, 2015 Jul 3. PMID 25969537, Free PMC Article
    3. Growth signalling pathways in Arabidopsis and the AGC protein kinases. Bögre L, et al. Trends Plant Sci, 2003 Sep. PMID 13678909
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_111890.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    3-phosphoinositide-dependent protein kinase
    NP_187665.2
    • 3-phosphoinositide-dependent protein kinase; FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Serine/threonine-protein kinase-1, 3-phosphoinositide dependent (InterPro:IPR015746), Protein kinase, catalytic domain (InterPro:IPR000719), Pleckstrin homology-type (InterPro:IPR011993); BEST Arabidopsis thaliana protein match is: 3'-phosphoinositide-dependent protein kinase 1 (TAIR:AT5G04510.1); Has 127579 Blast hits to 125597 proteins in 4638 species: Archae - 184; Bacteria - 15229; Metazoa - 47076; Fungi - 13122; Plants - 29847; Viruses - 648; Other Eukaryotes - 21473 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3289677..3292909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111890.4 → NP_187665.2  3-phosphoinositide-dependent protein kinase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187665.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WSV2, Q4V3C8, Q9SQY4
      UniProtKB/TrEMBL
      A0A178VK02
      Conserved Domains (3) summary
      smart00220
      Location:45 → 312
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05581
      Location:43 → 312
      STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
      pfam14593
      Location:383 → 486
      PH_3; PH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V3C8.1

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