U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    OMR1 L-O-methylthreonine resistant 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820166, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    OMR1
    Official Full Name
    L-O-methylthreonine resistant 1
    Primary source
    TAIR:AT3G10050
    Locus tag
    AT3G10050
    See related
    Araport:AT3G10050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    L-O-methylthreonine resistant 1; THREONINE DEHYDRATASE/DEAMINASE
    Summary
    first enzyme in the biosynthetic pathway of isoleucine
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See OMR1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (3098725..3102048, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene tRNA-Arg Neighboring gene sequence-specific DNA binding transcription factor Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene TBP-associated factor 12 Neighboring gene RmlC-like cupins superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. L-O-Methylthreonine-Resistant Mutant of Arabidopsis Defective in Isoleucine Feedback Regulation. Mourad G, et al. Plant Physiol, 1995 Jan. PMID 12228340, Free PMC Article
    2. Arabidopsis methionine gamma-lyase is regulated according to isoleucine biosynthesis needs but plays a subordinate role to threonine deaminase. Joshi V, et al. Plant Physiol, 2009 Sep. PMID 19571310, Free PMC Article
    3. Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids. Niehaus TD, et al. Plant Cell, 2014 Jul. PMID 25070638, Free PMC Article
    4. A Regulatory Hierarchy of the Arabidopsis Branched-Chain Amino Acid Metabolic Network. Xing A, et al. Plant Cell, 2017 Jun. PMID 28522547, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    NM_111840.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables threonine deaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables threonine deaminase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in isoleucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within isoleucine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within isoleucine biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    L-O-methylthreonine resistant 1
    NP_187616.1
    • L-O-methylthreonine resistant 1 (OMR1); FUNCTIONS IN: L-threonine ammonia-lyase activity; INVOLVED IN: isoleucine biosynthetic process, threonine metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Threonine dehydratase I (InterPro:IPR005787), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Threonine dehydratase, C-terminal (InterPro:IPR001721), Serine/threonine dehydratase, pyridoxal-phosphate-binding site (InterPro:IPR000634); BEST Arabidopsis thaliana protein match is: serine racemase (TAIR:AT4G11640.1); Has 26917 Blast hits to 26860 proteins in 2759 species: Archae - 692; Bacteria - 18712; Metazoa - 552; Fungi - 889; Plants - 577; Viruses - 2; Other Eukaryotes - 5493 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3098725..3102048 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111840.3 → NP_187616.1  L-O-methylthreonine resistant 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187616.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SPF1, Q9ZSS6
      UniProtKB/TrEMBL
      A0A178VHF4, A0A5S9XAY2, Q8GUG5
      Conserved Domains (1) summary
      PLN02550
      Location:1 → 592
      PLN02550; threonine dehydratase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZSS6.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools