MORF1 multiple organellar RNA editing factor [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: MORF1
Official Full Name: multiple organellar RNA editing factor
Primary source: TAIR:AT4G20020
Locus tag: AT4G20020
See related: Araport:AT4G20020
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F18F4.120; F18F4_120; multiple organellar RNA editing factor 1
Summary: Encodes a protein involved in RNA editing in mitochondria.
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Genomic context

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See MORF1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 5

Sequence:: Chromosome: 4; NC_003075.7 (10844131..10846163, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

With the MORF1 and MORF9 structures we elucidate a yet unknown fold, corroborate MORF interaction studies, validate the mechanism of MORF multimerization by structure-based mutants and pave the way towards a complete structural characterization of the plant RNA editosome.
Title: Crystal structures of the Arabidopsis thaliana organellar RNA editing factors MORF1 and MORF9.
Submolecular analysis of the MORF1 protein reveals that the MORF-MORF protein connections require the C-terminal region of the central conserved MORF box. [MORF1]
Title: Selective homo- and heteromer interactions between the multiple organellar RNA editing factor (MORF) proteins in Arabidopsis thaliana.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_118121.4

Supported by ESTs:

NM_202850.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein dimerization activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within chloroplast RNA modification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cytidine to uridine editing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitochondrial RNA modification	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in mitochondrion	HDA more info	PubMed
colocalizes_with mitochondrion	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: multiple organellar RNA editing factor

NP_193735.1

unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G44780.1); Has 28928 Blast hits to 16023 proteins in 1033 species: Archae - 4; Bacteria - 4155; Metazoa - 15463; Fungi - 2938; Plants - 3091; Viruses - 205; Other Eukaryotes - 3072 (source: NCBI BLink).

NP_974579.1

unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G44780.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

10844131..10846163 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_202850.3 → NP_974579.1 multiple organellar RNA editing factor [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_974579.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V370, A0A5S9XU51

Conserved Domains (1) summary

pfam09606
Location:202 → 381

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
NM_118121.4 → NP_193735.1 multiple organellar RNA editing factor [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193735.1

Status: REVIEWED

UniProtKB/Swiss-Prot

F4JU25, O49429

UniProtKB/TrEMBL

A0A178V370, A0A5S9XU51

Conserved Domains (1) summary

pfam09606
Location:202 → 381

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal