DHS1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: DHS1
Official Full Name: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1
Primary source: TAIR:AT4G39980
Locus tag: AT4G39980
See related: Araport:AT4G39980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1; 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE 1; 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE 1; AtDAHP1; DAHP1; T5J17.150; T5J17_150
Summary: Encodes a 2-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, which catalyzes the first committed step in aromatic amino acid biosynthesis. Gene expression is induced by wounding and pathogenic bacteria Pseudomonas syringae.
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Genomic context

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See DHS1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 5

Sequence:: Chromosome: 4; NC_003075.7 (18539511..18542122)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

MASC_STS15199 (e-PCR)
- UniSTS:258783

MASC_STS15351 (e-PCR)
- UniSTS:258795

NM_120162.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables 3-deoxy-7-phosphoheptulonate synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables 3-deoxy-7-phosphoheptulonate synthase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables 3-deoxy-7-phosphoheptulonate synthase activity	TAS Traceable Author Statement more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within aromatic amino acid family biosynthetic process	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within chorismate biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in chorismate biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chorismate biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to bacterium	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to wounding	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast	TAS Traceable Author Statement more info	PubMed
located_in mitochondrion	HDA more info	PubMed

General protein information

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Preferred Names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1

NP_195708.1

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1 (DHS1); CONTAINS InterPro DOMAIN/s: DAHP synthetase, class II (InterPro:IPR002480); BEST Arabidopsis thaliana protein match is: Class-II DAHP synthetase family protein (TAIR:AT1G22410.1); Has 3797 Blast hits to 3784 proteins in 681 species: Archae - 0; Bacteria - 1224; Metazoa - 0; Fungi - 110; Plants - 172; Viruses - 0; Other Eukaryotes - 2291 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

18539511..18542122

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_120162.5 → NP_195708.1 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195708.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P29976, Q9SMQ7

UniProtKB/TrEMBL

A0A178UXE4

Conserved Domains (1) summary

PLN02291
Location:49 → 525

PLN02291; phospho-2-dehydro-3-deoxyheptonate aldolase