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    OVA1 methionyl-tRNA synthetase / methionine-tRNA ligase / MetRS (cpMetRS) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824706, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OVA1
    Official Full Name
    methionyl-tRNA synthetase / methionine-tRNA ligase / MetRS (cpMetRS)
    Primary source
    TAIR:AT3G55400
    Locus tag
    AT3G55400
    See related
    Araport:AT3G55400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    OVULE ABORTION 1
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    Genomic context

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    See OVA1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Sequence:
    Chromosome: 3; NC_003074.8 (20535631..20539138, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme 14 Neighboring gene ncRNA Neighboring gene Uncharacterized protein family (UPF0497) Neighboring gene 2-oxoglutarate dehydrogenase, E1 component Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A single gene of chloroplast origin codes for mitochondrial and chloroplastic methionyl-tRNA synthetase in Arabidopsis thaliana. Menand B, et al. Proc Natl Acad Sci U S A, 1998 Sep 1. PMID 9724821, Free PMC Article
    2. Dual targeting is the rule for organellar aminoacyl-tRNA synthetases in Arabidopsis thaliana. Duchêne AM, et al. Proc Natl Acad Sci U S A, 2005 Nov 8. PMID 16251277, Free PMC Article
    3. Requirement of aminoacyl-tRNA synthetases for gametogenesis and embryo development in Arabidopsis. Berg M, et al. Plant J, 2005 Dec. PMID 16297076
    4. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084826.2
    NM_115398.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methionine-tRNA ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methionine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methionyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within plant ovule development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methionyl-tRNA synthetase / methionine-tRNA ligase / MetRS (cpMetRS)
    NP_001078295.1
    • OVULE ABORTION 1 (OVA1); FUNCTIONS IN: methionine-tRNA ligase activity, aminoacyl-tRNA ligase activity, ATP binding; INVOLVED IN: tRNA aminoacylation for protein translation, ovule development; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Methionyl-tRNA synthetase, class Ia, N-terminal (InterPro:IPR014758), Aminoacyl-tRNA synthetase, class I (M) (InterPro:IPR015413), Methionyl-tRNA synthetase, class Ia (InterPro:IPR002304), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080); BEST Arabidopsis thaliana protein match is: methionine--tRNA ligase, putative / methionyl-tRNA synthetase, putative / MetRS, putative (TAIR:AT4G13780.1); Has 24900 Blast hits to 23813 proteins in 3001 species: Archae - 930; Bacteria - 15835; Metazoa - 410; Fungi - 530; Plants - 181; Viruses - 3; Other Eukaryotes - 7011 (source: NCBI BLink).
    NP_191100.1
    • OVULE ABORTION 1 (OVA1); FUNCTIONS IN: methionine-tRNA ligase activity, aminoacyl-tRNA ligase activity, ATP binding; INVOLVED IN: tRNA aminoacylation for protein translation, ovule development; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR013155), Methionyl-tRNA synthetase, class Ia, N-terminal (InterPro:IPR014758), Aminoacyl-tRNA synthetase, class I (M) (InterPro:IPR015413), Methionyl-tRNA synthetase, class Ia (InterPro:IPR002304), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080); BEST Arabidopsis thaliana protein match is: methionine--tRNA ligase, putative / methionyl-tRNA synthetase, putative / MetRS, putative (TAIR:AT4G13780.1); Has 26528 Blast hits to 25030 proteins in 3018 species: Archae - 991; Bacteria - 17017; Metazoa - 429; Fungi - 593; Plants - 193; Viruses - 3; Other Eukaryotes - 7302 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20535631..20539138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115398.3 → NP_191100.1  methionyl-tRNA synthetase / methionine-tRNA ligase / MetRS (cpMetRS) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191100.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23761, Q9ASP8, Q9M2T9
      UniProtKB/TrEMBL
      A0A5S9XL54, A0A654FG02
      Conserved Domains (3) summary
      cd07957
      Location:414 → 544
      Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
      cd00814
      Location:70 → 405
      MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
      PLN02224
      Location:1 → 616
      PLN02224; methionine-tRNA ligase

    2. NM_001084826.2 → NP_001078295.1  methionyl-tRNA synthetase / methionine-tRNA ligase / MetRS (cpMetRS) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078295.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VFX8, A8MRF2
      Conserved Domains (3) summary
      cd00814
      Location:70 → 405
      MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
      pfam09334
      Location:71 → 429
      tRNA-synt_1g; tRNA synthetases class I (M)
      cl12020
      Location:414 → 516
      Anticodon_Ia_like; Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M2T9.1

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