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    SDIR1 RING/U-box superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824718, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SDIR1
    Official Full Name
    RING/U-box superfamily protein
    Primary source
    TAIR:AT3G55530
    Locus tag
    AT3G55530
    See related
    Araport:AT3G55530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtSDIR1; SALT- AND DROUGHT-INDUCED RING FINGER1
    Summary
    Encodes an intracellular membrane localized protein with E3 ligase activity that is involved in regulation of ABA signaling. Loss of function alleles show decreased sensitivity to ABA. Overexpression results in increased sensitivity to ABA.
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    Genomic context

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    See SDIR1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (20595126..20597603, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ROTUNDIFOLIA like 7 Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nuclear transport factor 2 (NTF2) family protein Neighboring gene Concanavalin A-like lectin protein kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis SDIR1 enhances drought tolerance in crop plants. Zhang YY, et al. Biosci Biotechnol Biochem, 2008 Aug. PMID 18685183
    2. SDIR1 is a RING finger E3 ligase that positively regulates stress-responsive abscisic acid signaling in Arabidopsis. Zhang Y, et al. Plant Cell, 2007 Jun. PMID 17573536, Free PMC Article
    3. Proteasomal Degradation of JAZ9 by Salt- and Drought-Induced Ring Finger 1 During Pathogen Infection. Ramu VS, et al. Mol Plant Microbe Interact, 2021 Dec. PMID 34615361
    4. The RING finger ubiquitin E3 ligase SDIR1 targets SDIR1-INTERACTING PROTEIN1 for degradation to modulate the salt stress response and ABA signaling in Arabidopsis. Zhang H, et al. Plant Cell, 2015 Jan. PMID 25616872, Free PMC Article
    5. The RING E3 ligase SDIR1 destabilizes EBF1/EBF2 and modulates the ethylene response to ambient temperature fluctuations in Arabidopsis. Hao D, et al. Proc Natl Acad Sci U S A, 2021 Feb 9. PMID 33526703, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Proteasomal Degradation of JAZ9 by Salt- and Drought-Induced Ring Finger 1 During Pathogen Infection.
      Title: Proteasomal Degradation of JAZ9 by Salt- and Drought-Induced Ring Finger 1 During Pathogen Infection.
    2. The RING E3 ligase SDIR1 destabilizes EBF1/EBF2 and modulates the ethylene response to ambient temperature fluctuations in Arabidopsis.
      Title: The RING E3 ligase SDIR1 destabilizes EBF1/EBF2 and modulates the ethylene response to ambient temperature fluctuations in Arabidopsis.
    3. SDIR1 can function as a drought-tolerance gene in both dicotyledons and monocotyledons, and that it can serve as a drought-tolerance engineering candidate gene in crop plants
      Title: Arabidopsis SDIR1 enhances drought tolerance in crop plants.
    4. SDIR1 (SALT- AND DROUGHT-INDUCED RING FINGER1) is a positive regulator of the ABA-dependent stress signaling pathway. [SDIR1]
      Title: SDIR1 is a RING finger E3 ligase that positively regulates stress-responsive abscisic acid signaling in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_115410.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RING/U-box superfamily protein
    NP_191112.1
    • SALT- AND DROUGHT-INDUCED RING FINGER1 (SDIR1); CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT1G04790.1); Has 9775 Blast hits to 9747 proteins in 287 species: Archae - 0; Bacteria - 6; Metazoa - 2690; Fungi - 760; Plants - 4971; Viruses - 89; Other Eukaryotes - 1259 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20595126..20597603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115410.3 → NP_191112.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191112.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M2S6
      UniProtKB/TrEMBL
      A0A178V9G1, A0A7G2EWZ6
      Conserved Domains (1) summary
      cd16454
      Location:210 → 252
      RING-H2_PA-TM-RING; RING finger, H2 subclass, found in the PA-TM-RING ubiquitin ligase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M2S6.1

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