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    TIP2;3 tonoplast intrinsic protein 2;3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834794, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIP2;3
    Official Full Name
    tonoplast intrinsic protein 2;3
    Primary source
    TAIR:AT5G47450
    Locus tag
    AT5G47450
    See related
    Araport:AT5G47450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA TONOPLAST INTRINSIC PROTEIN 2;3; ATTIP2;3; DELTA-TIP3; DELTA-TONOPLAST INTRINSIC PROTEIN 3; MNJ7.4; MNJ7_4; tonoplast intrinsic protein 2;3
    Summary
    Tonoplast intrinsic protein, transports ammonium (NH3) and methylammonium across the tonoplast membrane, gene expression shows diurnal regulation and is upregulated by ammonium (NH3).
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    Genomic context

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    See TIP2;3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (19248249..19249622, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene formyltetrahydrofolate deformylase Neighboring gene auxin canalization protein (DUF828) Neighboring gene pseudo Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tonoplast intrinsic proteins AtTIP2;1 and AtTIP2;3 facilitate NH3 transport into the vacuole. Loqué D, et al. Plant Physiol, 2005 Feb. PMID 15665250, Free PMC Article
    2. In vivo imaging of the tonoplast intrinsic protein family in Arabidopsis roots. Gattolin S, et al. BMC Plant Biol, 2009 Nov 18. PMID 19922653, Free PMC Article
    3. The Arabidopsis abiotic stress-induced TSPO-related protein reduces cell-surface expression of the aquaporin PIP2;7 through protein-protein interactions and autophagic degradation. Hachez C, et al. Plant Cell, 2014 Dec. PMID 25538184, Free PMC Article
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124117.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ammonium channel activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methylammonium transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables water channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in central vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tonoplast intrinsic protein 2;3
    NP_199556.1
    • tonoplast intrinsic protein 2;3 (TIP2;3); CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: tonoplast intrinsic protein 2;2 (TAIR:AT4G17340.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19248249..19249622 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124117.3 → NP_199556.1  tonoplast intrinsic protein 2;3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199556.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WNU5, Q53XE4, Q9FGL2
      UniProtKB/TrEMBL
      A0A178UJ23, A0A5S9YC53, A0A654G9D2
      Conserved Domains (1) summary
      PLN00166
      Location:1 → 250
      PLN00166; aquaporin TIP2; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FGL2.1

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