U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FTSH11 FTSH protease 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835398, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FTSH11
    Official Full Name
    FTSH protease 11
    Primary source
    TAIR:AT5G53170
    Locus tag
    AT5G53170
    See related
    Araport:AT5G53170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    FTSH protease 11; MFH8.11; MFH8_11
    Summary
    encodes an FtsH protease that is localized to the chloroplast and the mitochondrion
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FTSH11 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    17
    Sequence:
    Chromosome: 5; NC_003076.8 (21562718..21568023, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene regulatory components of ABA receptor 3 Neighboring gene polypyrimidine tract-binding protein 2 Neighboring gene Nodulin MtN3 family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Chlorophyll fluorescence analysis revealed essential roles of FtsH11 protease in regulation of the adaptive responses of photosynthetic systems to high temperature. Chen J, et al. BMC Plant Biol, 2018 Jan 10. PMID 29320985, Free PMC Article
    2. Deletion of FtsH11 protease has impact on chloroplast structure and function in Arabidopsis thaliana when grown under continuous light. Wagner R, et al. Plant Cell Environ, 2016 Nov. PMID 27479913
    3. The gene complement for proteolysis in the cyanobacterium Synechocystis sp. PCC 6803 and Arabidopsis thaliana chloroplasts. Sokolenko A, et al. Curr Genet, 2002 Aug. PMID 12185496
    4. FtsH11 protease plays a critical role in Arabidopsis thermotolerance. Chen J, et al. Plant J, 2006 Oct. PMID 16972866
    5. Plant mitochondria contain at least two i-AAA-like complexes. Urantowka A, et al. Plant Mol Biol, 2005 Sep. PMID 16247555

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtFtsH11 is essential for normal photosynthetic function under moderately elevated temperatures. The network mediated by AtFtsH11 protease plays critical roles for maintaining the thermostability and possibly structural integrity of both photosystems under elevated temperatures.
      Title: Chlorophyll fluorescence analysis revealed essential roles of FtsH11 protease in regulation of the adaptive responses of photosynthetic systems to high temperature.
    2. FtsH11 is crucial for chloroplast structure and function during growth in prolonged photoperiod.
      Title: Deletion of FtsH11 protease has impact on chloroplast structure and function in Arabidopsis thaliana when grown under continuous light.
    3. AtFtsH4 is an exclusively mitochondrial protein while AtFtsH11 is found in both chloroplasts and mitochondria.
      Title: Plant mitochondria contain at least two i-AAA-like complexes.
    4. The A. thaliana FtsH11-encoded protease has a direct role in thermotolerance.
      Title: FtsH11 protease plays a critical role in Arabidopsis thermotolerance.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help
    NM_124696.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent peptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within PSII associated light-harvesting complex II catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in response to high light intensity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    FTSH protease 11
    NP_568787.1
    • FTSH protease 11 (FTSH11); FUNCTIONS IN: metallopeptidase activity, ATP-dependent peptidase activity, ATPase activity; INVOLVED IN: response to heat, PSII associated light-harvesting complex II catabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642); BEST Arabidopsis thaliana protein match is: FTSH protease 4 (TAIR:AT2G26140.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21562718..21568023 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124696.4 → NP_568787.1  FTSH protease 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568787.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FGM0
      UniProtKB/TrEMBL
      A0A178UR45, A0A5S9YDI8
      Conserved Domains (1) summary
      TIGR01241
      Location:355 → 784
      FtsH_fam; ATP-dependent metalloprotease FtsH
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FGM0.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools