U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ACT4 actin 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836056, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ACT4
    Official Full Name
    actin 4
    Primary source
    TAIR:AT5G59370
    Locus tag
    AT5G59370
    See related
    Araport:AT5G59370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin 4; F2O15.3; F2O15_3
    Summary
    Encodes one of eight Arabidopsis actins. ACT4 belongs to the reproductive actin subclass which is predominantly expressed in developing and reproductive tissues, such as pollen, pollen tubes, ovules, and developing seeds. Expression of the ACT4/GUS fusion was restricted to young vascular tissues, tapetum, and developing and mature pollen.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ACT4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (23949661..23951837)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene methyl-CPG-binding domain 6 Neighboring gene tRNA-Gly

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Arabidopsis thaliana ACT4/ACT12 actin gene subclass is strongly expressed throughout pollen development. Huang S, et al. Plant J, 1996 Aug. PMID 8771777
    2. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    NM_001085300.1
    NM_125328.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables structural constituent of cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization TAS
    Traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    actin 4
    NP_001078769.1
    • actin 4 (ACT4); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: actin cytoskeleton organization; LOCATED IN: mitochondrion; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Actin, conserved site (InterPro:IPR004001), Actin/actin-like (InterPro:IPR004000), Actin/actin-like conserved site (InterPro:IPR020902); BEST Arabidopsis thaliana protein match is: actin-12 (TAIR:AT3G46520.1); Has 15130 Blast hits to 14740 proteins in 3013 species: Archae - 8; Bacteria - 8; Metazoa - 5679; Fungi - 5217; Plants - 1603; Viruses - 2; Other Eukaryotes - 2613 (source: NCBI BLink).
    NP_200745.1
    • actin 4 (ACT4); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: actin cytoskeleton organization; LOCATED IN: mitochondrion; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Actin, conserved site (InterPro:IPR004001), Actin/actin-like (InterPro:IPR004000), Actin/actin-like conserved site (InterPro:IPR020902); BEST Arabidopsis thaliana protein match is: actin-12 (TAIR:AT3G46520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23949661..23951837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125328.4 → NP_200745.1  actin 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200745.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P53494
      UniProtKB/TrEMBL
      A0A178ULX8, A0A178VHX9, A0A5S9XJ21, Q84W24
      Conserved Domains (1) summary
      cl17037
      Location:5 → 377
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    2. NM_001085300.1 → NP_001078769.1  actin 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078769.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P53494
      UniProtKB/TrEMBL
      A0A178ULX8, A0A178VHX9, A0A5S9XJ21, Q84W24
      Conserved Domains (1) summary
      cl17037
      Location:5 → 377
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53494.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools