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    Alg9-like mannosyltransferase family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831337, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Alg9-like mannosyltransferase family
    Primary source
    TAIR:AT5G14850
    Locus tag
    AT5G14850
    See related
    Araport:AT5G14850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    abnormal pollen tube guidance 1; APTG1; T9L3.150; T9L3_150
    Summary
    Encodes a putative mannosyltransferase homolog to human PIG-B and yeast GPI10, both of which are involved in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. Disruption of the gene affects COBRA-LIKE10 localization, a GPI-anchored protein (GPI-AP) important for pollen tube growth and guidance.
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (4801870..4805036, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene cyclic nucleotide-gated channel 18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ABNORMAL POLLEN TUBE GUIDANCE1, an Endoplasmic Reticulum-Localized Mannosyltransferase Homolog of GLYCOSYLPHOSPHATIDYLINOSITOL10 in Yeast and PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS B in Human, Is Required for Arabidopsis Pollen Tube Micropylar Guidance and Embryo Development. Dai XR, et al. Plant Physiol, 2014 Aug. PMID 24963069, Free PMC Article
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001343373.1
    NM_001343374.1
    NM_001343375.1
    NM_001343376.1
    NM_121489.2
    NM_180491.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables mannosyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in attachment of GPI anchor to protein IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in pollen tube IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Alg9-like mannosyltransferase family
    NP_568305.1
    • Alg9-like mannosyltransferase family; FUNCTIONS IN: mannosyltransferase activity, transferase activity, transferring glycosyl groups; INVOLVED IN: GPI anchor biosynthetic process, GPI anchor metabolic process; LOCATED IN: endoplasmic reticulum membrane, intrinsic to endoplasmic reticulum membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Alg9-like mannosyltransferase (InterPro:IPR005599); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_850822.1
    • Alg9-like mannosyltransferase family; FUNCTIONS IN: mannosyltransferase activity, transferase activity, transferring glycosyl groups; INVOLVED IN: GPI anchor biosynthetic process, GPI anchor metabolic process; LOCATED IN: endoplasmic reticulum membrane, intrinsic to endoplasmic reticulum membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Alg9-like mannosyltransferase (InterPro:IPR005599); Has 1101 Blast hits to 1081 proteins in 222 species: Archae - 0; Bacteria - 46; Metazoa - 380; Fungi - 409; Plants - 121; Viruses - 0; Other Eukaryotes - 145 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4801870..4805036 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121489.2 → NP_568305.1  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568305.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94A15, Q9LEQ5
      UniProtKB/TrEMBL
      A0A178UBV6, A0A7G2FDQ7
      Conserved Domains (1) summary
      PLN02816
      Location:1 → 545
      PLN02816; mannosyltransferase

    2. NM_001343373.1 → NP_001331178.1  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UBV6, A0A1P8BD32

    3. NM_001343375.1 → NP_001331181.1  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UBV6, A0A1P8BD62

    4. NM_001343374.1 → NP_001331180.1  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BD29

    5. NM_180491.1 → NP_850822.1  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850822.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UBV6, F4K887
      Conserved Domains (1) summary
      PLN02816
      Location:1 → 529
      PLN02816; mannosyltransferase

    6. NM_001343376.1 → NP_001331179.1  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BD29
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94A15.1

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