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    UCP5 uncoupling protein 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816783, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UCP5
    Official Full Name
    uncoupling protein 5
    Primary source
    TAIR:AT2G22500
    Locus tag
    AT2G22500
    See related
    Araport:AT2G22500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPUMP5; DIC1; DICARBOXYLATE CARRIER 1; F14M13.10; F14M13_10; PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 5; uncoupling protein 5
    Summary
    Encodes one of the mitochondrial dicarboxylate carriers (DIC): DIC1 (AT2G22500), DIC2 (AT4G24570), DIC3 (AT5G09470).
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    Genomic context

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    See UCP5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (9562774..9564850, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene uncharacterized protein Neighboring gene Alkaline-phosphatase-like family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The plant energy-dissipating mitochondrial systems: depicting the genomic structure and the expression profiles of the gene families of uncoupling protein and alternative oxidase in monocots and dicots. Borecky J, et al. J Exp Bot, 2006. PMID 16473895
    2. Molecular identification of three Arabidopsis thaliana mitochondrial dicarboxylate carrier isoforms: organ distribution, bacterial expression, reconstitution into liposomes and functional characterization. Palmieri L, et al. Biochem J, 2008 Mar 15. PMID 18039180
    3. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Miscellaneous features

    • Loc: c9564686-9564579 AT2G22500.uORF1
    NM_127816.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables dicarboxylic acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidative phosphorylation uncoupler activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within mitochondrial transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in proton transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncoupling protein 5
    NP_179836.1
    • uncoupling protein 5 (UCP5); FUNCTIONS IN: binding, dicarboxylic acid transmembrane transporter activity; INVOLVED IN: transport, mitochondrial transport; LOCATED IN: mitochondrion, mitochondrial inner membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial brown fat uncoupling protein (InterPro:IPR002030), Mitochondrial substrate/solute carrier (InterPro:IPR018108); BEST Arabidopsis thaliana protein match is: dicarboxylate carrier 2 (TAIR:AT4G24570.1); Has 25222 Blast hits to 13203 proteins in 454 species: Archae - 0; Bacteria - 2; Metazoa - 10525; Fungi - 7328; Plants - 4898; Viruses - 0; Other Eukaryotes - 2469 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9562774..9564850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127816.3 → NP_179836.1  uncoupling protein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179836.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WL82, Q94K32, Q9SJY5
      UniProtKB/TrEMBL
      A0A178W292, A0A5S9X074, Q8LDF6
      Conserved Domains (1) summary
      pfam00153
      Location:216 → 311
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJY5.1

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