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    5PTase14 endonuclease/exonuclease/phosphatase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817740, updated on 18-Sep-2024

    Summary

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    Official Symbol
    5PTase14
    Official Full Name
    endonuclease/exonuclease/phosphatase family protein
    Primary source
    TAIR:AT2G31830
    Locus tag
    AT2G31830
    See related
    Araport:AT2G31830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20M17.13; F20M17_13; inositol-polyphosphate 5-phosphatase 14
    Summary
    Encodes a 5-inositol-polyphosphate phosphatase, that, in vitro, shows some activity against Ins(1,4,5)P3 and PI(3,4,5)P3, but even higher activity against PI(4,5)P2
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    Genomic context

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    See 5PTase14 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (13532483..13537800, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene Integrin-linked protein kinase family Neighboring gene ACT domain-containing small subunit of acetolactate synthase protein Neighboring gene Ankyrin repeat family protein Neighboring gene Thioredoxin superfamily protein Neighboring gene uncharacterized protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular and biochemical characterization of three WD-repeat-domain-containing inositol polyphosphate 5-phosphatases in Arabidopsis thaliana. Zhong R, et al. Plant Cell Physiol, 2004 Nov. PMID 15574849
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inositol-1,4,5-trisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within inositol phosphate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    endonuclease/exonuclease/phosphatase family protein
    NP_001189651.1
    • endonuclease/exonuclease/phosphatase family protein; FUNCTIONS IN: inositol or phosphatidylinositol phosphatase activity; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135), Quinoprotein amine dehydrogenase, beta chain-like (InterPro:IPR011044); BEST Arabidopsis thaliana protein match is: Endonuclease/exonuclease/phosphatase family protein (TAIR:AT1G05630.2).
    NP_180742.1
    • endonuclease/exonuclease/phosphatase family protein; FUNCTIONS IN: inositol or phosphatidylinositol phosphatase activity; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), WD40 repeat (InterPro:IPR001680), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135), Quinoprotein amine dehydrogenase, beta chain-like (InterPro:IPR011044); BEST Arabidopsis thaliana protein match is: Endonuclease/exonuclease/phosphatase family protein (TAIR:AT1G05630.2); Has 2284 Blast hits to 2227 proteins in 249 species: Archae - 0; Bacteria - 34; Metazoa - 850; Fungi - 543; Plants - 566; Viruses - 0; Other Eukaryotes - 291 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13532483..13537800 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128741.3 → NP_180742.1  endonuclease/exonuclease/phosphatase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180742.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SKB7
      UniProtKB/TrEMBL
      A0A5S9X3J9, A0A654EXZ0
      Conserved Domains (4) summary
      cd09074
      Location:580 → 926
      INPP5c; Catalytic domain of inositol polyphosphate 5-phosphatases
      COG2319
      Location:218 → 384
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:451 → 484
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:449 → 533
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001202722.1 → NP_001189651.1  endonuclease/exonuclease/phosphatase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189651.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EXZ0, F4IRT2
      Conserved Domains (4) summary
      cd09074
      Location:580 → 926
      INPP5c; Catalytic domain of inositol polyphosphate 5-phosphatases
      COG2319
      Location:218 → 384
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:451 → 484
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:449 → 533
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_001336348.1 → NP_001324125.1  endonuclease/exonuclease/phosphatase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VTH3, A0A1P8AZ51
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SKB7.1

    Gene LinkOut

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