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    TEJ Poly (ADP-ribose) glycohydrolase (PARG) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817745, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TEJ
    Official Full Name
    Poly (ADP-ribose) glycohydrolase (PARG)
    Primary source
    TAIR:AT2G31870
    Locus tag
    AT2G31870
    See related
    Araport:AT2G31870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20M17.9; F20M17_9; PARG1; poly(ADP-ribose) glycohydrolase 1; Sanskrit for 'bright'
    Summary
    The gene encodes a poly(ADPribose) glycohydrolase (PARG1). Mutant analysis revealed that PARG1 PARG1 plays a role in abiotic stress responses.
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    Genomic context

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    See TEJ in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (13549861..13553844, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene B3 domain protein Neighboring gene poly(ADP-ribose) glycohydrolase 2 Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene ncRNA Neighboring gene RAP Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis poly(ADP-ribose) glycohydrolase 1 is required for drought, osmotic and oxidative stress responses. Li G, et al. Plant Sci, 2011 Feb. PMID 21421372
    2. tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator. Panda S, et al. Dev Cell, 2002 Jul. PMID 12110167
    3. PARG1 and EXA1 genes as possible components of the facultative epigenetic control of plant development. Kupriyanova E, et al. Physiol Plant, 2023 Jul-Aug. PMID 37350155
    4. Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation. Zhang H, et al. Sci Rep, 2015 Oct 30. PMID 26516022, Free PMC Article
    5. Disruption of poly(ADP-ribosyl)ation mechanisms alters responses of Arabidopsis to biotic stress. Adams-Phillips L, et al. Plant Physiol, 2010 Jan. PMID 19889874, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PARG1 and EXA1 genes as possible components of the facultative epigenetic control of plant development.
      Title: PARG1 and EXA1 genes as possible components of the facultative epigenetic control of plant development.
    2. PARG1 antagonistically modulates the DNA repair process by preventing the over-induction of DNA repair genes.
      Title: Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084520.1
    NM_128745.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables poly(ADP-ribose) glycohydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables poly(ADP-ribose) glycohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables poly(ADP-ribose) glycohydrolase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Poly (ADP-ribose) glycohydrolase (PARG)
    NP_001077989.1
    • Sanskrit for 'bright' (TEJ); CONTAINS InterPro DOMAIN/s: Poly(ADP-ribose) glycohydrolase (InterPro:IPR007724); BEST Arabidopsis thaliana protein match is: poly(ADP-ribose) glycohydrolase 2 (TAIR:AT2G31865.2); Has 549 Blast hits to 374 proteins in 97 species: Archae - 0; Bacteria - 0; Metazoa - 324; Fungi - 12; Plants - 58; Viruses - 0; Other Eukaryotes - 155 (source: NCBI BLink).
    NP_565730.1
    • Sanskrit for 'bright' (TEJ); CONTAINS InterPro DOMAIN/s: Poly(ADP-ribose) glycohydrolase (InterPro:IPR007724); BEST Arabidopsis thaliana protein match is: poly(ADP-ribose) glycohydrolase 2 (TAIR:AT2G31865.2); Has 554 Blast hits to 370 proteins in 95 species: Archae - 0; Bacteria - 0; Metazoa - 332; Fungi - 10; Plants - 60; Viruses - 0; Other Eukaryotes - 152 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13549861..13553844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084520.1 → NP_001077989.1  Poly (ADP-ribose) glycohydrolase (PARG) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077989.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MRN2
      Conserved Domains (1) summary
      pfam05028
      Location:83 → 491
      PARG_cat; Poly (ADP-ribose) glycohydrolase (PARG)

    2. NM_128745.3 → NP_565730.1  Poly (ADP-ribose) glycohydrolase (PARG) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565730.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56W82, Q94ET7, Q9SKB3
      UniProtKB/TrEMBL
      A0A5S9X314, A0A654EZE3
      Conserved Domains (1) summary
      pfam05028
      Location:83 → 489
      PARG_cat; Poly (ADP-ribose) glycohydrolase (PARG)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SKB3.2

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