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    PER1 1-cysteine peroxiredoxin 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841231, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PER1
    Official Full Name
    1-cysteine peroxiredoxin 1
    Primary source
    TAIR:AT1G48130
    Locus tag
    AT1G48130
    See related
    Araport:AT1G48130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    1-CYS PEROXIREDOXIN; 1-cysteine peroxiredoxin 1; ATPER1; F21D18.15; F21D18_15
    Summary
    encodes a protein similar to the 1-cysteine (1-Cys) peroxiredoxin family of antioxidants. Expression is limited to seed (aleurone and embryo) and is not induced by ABA or drought.
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    Genomic context

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    See PER1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (17780429..17781727)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Pectin lyase-like superfamily protein Neighboring gene evolutionarily conserved C-terminal region 7 Neighboring gene serine/threonine-protein phosphatase 7 long form-like protein Neighboring gene dolichol-phosphate mannosyltransferase-like protein Neighboring gene plant mobile domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtPER1 enhances primary seed dormancy and reduces seed germination by suppressing the ABA catabolism and GA biosynthesis in Arabidopsis seeds. Chen H, et al. Plant J, 2020 Jan. PMID 31536657
    2. The expression of a peroxiredoxin antioxidant gene, AtPer1, in Arabidopsis thaliana is seed-specific and related to dormancy. Haslekås C, et al. Plant Mol Biol, 1998 Apr. PMID 9580097
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtPER1 enhances primary seed dormancy and reduces seed germination by suppressing the ABA catabolism and GA biosynthesis in Arabidopsis seeds.
      Title: AtPER1 enhances primary seed dormancy and reduces seed germination by suppressing the ABA catabolism and GA biosynthesis in Arabidopsis seeds.
    Submit: New GeneRIF Correction

    General gene information

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    NM_103709.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables thioredoxin peroxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular oxidant detoxification IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within maintenance of seed dormancy TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to desiccation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    1-cysteine peroxiredoxin 1
    NP_175247.1
    • 1-cysteine peroxiredoxin 1 (PER1); FUNCTIONS IN: thioredoxin peroxidase activity, antioxidant activity; INVOLVED IN: maintenance of seed dormancy, response to desiccation; LOCATED IN: cellular_component unknown; EXPRESSED IN: embryo, aleurone layer, seed; EXPRESSED DURING: seed development stages; CONTAINS InterPro DOMAIN/s: Peroxiredoxin, C-terminal (InterPro:IPR019479), Thioredoxin fold (InterPro:IPR012335), Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (InterPro:IPR000866), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: 2-cysteine peroxiredoxin B (TAIR:AT5G06290.1); Has 11559 Blast hits to 11559 proteins in 2567 species: Archae - 531; Bacteria - 7064; Metazoa - 1157; Fungi - 321; Plants - 349; Viruses - 0; Other Eukaryotes - 2137 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17780429..17781727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103709.4 → NP_175247.1  1-cysteine peroxiredoxin 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175247.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04005, Q42319, Q84WE3
      UniProtKB/TrEMBL
      A0A178W968, A0A5S9WMM6
      Conserved Domains (1) summary
      cd03016
      Location:6 → 214
      PRX_1cys; Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04005.1

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