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    BRL3 BRI1-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820538, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BRL3
    Official Full Name
    BRI1-like 3
    Primary source
    TAIR:AT3G13380
    Locus tag
    AT3G13380
    See related
    Araport:AT3G13380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BRI1-like 3
    Summary
    Similar to BRI, brassinosteroid receptor protein.
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    Genomic context

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    See BRL3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (4346330..4350939)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene formin-like protein Neighboring gene ncRNA Neighboring gene SKU5 similar 11 Neighboring gene SKU5 similar 13 Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of the vascular brassinosteroid receptor BRL3 confers drought resistance without penalizing plant growth. Fàbregas N, et al. Nat Commun, 2018 Nov 8. PMID 30409967, Free PMC Article
    2. BRL3 and AtRGS1 cooperate to fine tune growth inhibition and ROS activation. Tunc-Ozdemir M, et al. PLoS One, 2017. PMID 28545052, Free PMC Article
    3. Binding of brassinosteroids to the extracellular domain of plant receptor kinase BRI1. Kinoshita T, et al. Nature, 2005 Jan 13. PMID 15650741
    4. The brassinosteroid insensitive1-like3 signalosome complex regulates Arabidopsis root development. Fàbregas N, et al. Plant Cell, 2013 Sep. PMID 24064770, Free PMC Article
    5. A role for brassinosteroid signalling in decision-making processes in the Arabidopsis seedling. Kalbfuß N, et al. PLoS Genet, 2022 Dec. PMID 36508461, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. this data suggests that manipulating BRL3 expression could be used to engineer drought tolerant crops.
      Title: Overexpression of the vascular brassinosteroid receptor BRL3 confers drought resistance without penalizing plant growth.
    2. BRL3 and AtRGS1 are part of a fine-tuning mechanism sensing glucose and flg22 to prevent excess ROS burst and control growth inhibition
      Title: BRL3 and AtRGS1 cooperate to fine tune growth inhibition and ROS activation.
    3. Genetic analysis of brl1 brl3 bak1-3 triple mutants revealed that BAK1, BRL1, and BRL3 signaling modulate root growth and development by contributing to the cellular activities of provascular and quiescent center cells.
      Title: The brassinosteroid insensitive1-like3 signalosome complex regulates Arabidopsis root development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_112183.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to light stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    BRI1-like 3
    NP_187946.1
    • BRI1-like 3 (BRL3); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: BRI1 like (TAIR:AT1G55610.2); Has 212526 Blast hits to 138151 proteins in 4666 species: Archae - 155; Bacteria - 20822; Metazoa - 67917; Fungi - 10742; Plants - 87364; Viruses - 306; Other Eukaryotes - 25220 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4346330..4350939
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112183.3 → NP_187946.1  BRI1-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187946.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DHZ3, C0LGN0, Q9LJF3
      UniProtKB/TrEMBL
      A0A5S9XBR3, A0A654F6R9
      Conserved Domains (2) summary
      PLN00113
      Location:32 → 1123
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:304 → 327
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LJF3.1

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