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    AT-HSFB2B winged-helix DNA-binding transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826771, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AT-HSFB2B
    Official Full Name
    winged-helix DNA-binding transcription factor family protein
    Primary source
    TAIR:AT4G11660
    Locus tag
    AT4G11660
    See related
    Araport:AT4G11660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HEAT SHOCK TRANSCRIPTION FACTOR B2B; HEAT SHOCK TRANSCRIPTION FACTOR B2B; HSF7; HSFB2B; T5C23.90; T5C23_90
    Summary
    member of Heat Stress Transcription Factor (Hsf) family
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    Genomic context

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    See AT-HSFB2B in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Sequence:
    Chromosome: 4; NC_003075.7 (7042354..7044708)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RALF-like 29 Neighboring gene Uncharacterized protein family (UPF0497) Neighboring gene ncRNA Neighboring gene DNA topoisomerase 4 subunit B (DUF810) Neighboring gene ncRNA Neighboring gene Zinc finger, C3HC4 type (RING finger) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HsfB2b-mediated repression of PRR7 directs abiotic stress responses of the circadian clock. Kolmos E, et al. Proc Natl Acad Sci U S A, 2014 Nov 11. PMID 25352668, Free PMC Article
    2. Arabidopsis HsfB1 and HsfB2b act as repressors of the expression of heat-inducible Hsfs but positively regulate the acquired thermotolerance. Ikeda M, et al. Plant Physiol, 2011 Nov. PMID 21908690, Free PMC Article
    3. XBAT31 regulates reproductive thermotolerance through controlling the accumulation of HSFB2a/B2b under heat stress conditions. Zhang LL, et al. Cell Rep, 2024 Jun 25. PMID 38870009
    4. A novel group of transcriptional repressors in Arabidopsis. Ikeda M, et al. Plant Cell Physiol, 2009 May. PMID 19324928
    5. Detection of in vivo interactions between Arabidopsis class A-HSFs, using a novel BiFC fragment, and identification of novel class B-HSF interacting proteins. Li M, et al. Eur J Cell Biol, 2010 Feb-Mar. PMID 19945192

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. XBAT31 regulates reproductive thermotolerance through controlling the accumulation of HSFB2a/B2b under heat stress conditions.
      Title: XBAT31 regulates reproductive thermotolerance through controlling the accumulation of HSFB2a/B2b under heat stress conditions.
    2. The constitutive expression of HsfB2b leads to severely reduced levels of the PRR7 transcript and late flowering and elongated hypocotyls.
      Title: HsfB2b-mediated repression of PRR7 directs abiotic stress responses of the circadian clock.
    3. These data indicate that HsfB1 and HsfB2b suppress the general heat shock response under non-heat-stress conditions and in the attenuating period.
      Title: Arabidopsis HsfB1 and HsfB2b act as repressors of the expression of heat-inducible Hsfs but positively regulate the acquired thermotolerance.
    4. Data suggest that HsfB1 and HsfB2b may be involved in complex regulatory networks, which are linked to other stress responses and signaling processes.
      Title: Detection of in vivo interactions between Arabidopsis class A-HSFs, using a novel BiFC fragment, and identification of novel class B-HSF interacting proteins.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_117235.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    winged-helix DNA-binding transcription factor family protein
    NP_192903.1
    • AT-HSFB2B; FUNCTIONS IN: transcription repressor activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: response to chitin; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Heat shock factor (HSF)-type, DNA-binding (InterPro:IPR000232); BEST Arabidopsis thaliana protein match is: heat shock transcription factor B2A (TAIR:AT5G62020.1); Has 32476 Blast hits to 10764 proteins in 847 species: Archae - 36; Bacteria - 10454; Metazoa - 9035; Fungi - 1651; Plants - 6330; Viruses - 666; Other Eukaryotes - 4304 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      7042354..7044708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117235.5 → NP_192903.1  winged-helix DNA-binding transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192903.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SCW3, Q9T0D3
      UniProtKB/TrEMBL
      A0A178UZH9, A0A5S9XRD6
      Conserved Domains (1) summary
      smart00415
      Location:57 → 149
      HSF; heat shock factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9T0D3.1

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