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    TPS12 terpenoid synthase 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826958, updated on 18-Sep-2024

    Summary

    Official Symbol
    TPS12
    Official Full Name
    terpenoid synthase 12
    Primary source
    TAIR:AT4G13280
    Locus tag
    AT4G13280
    See related
    Araport:AT4G13280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTPS12; T9E8.20; T9E8_20; terpenoid synthase 12
    Summary
    Catalyzes the conversion of farnesyl diphosphate to (Z)-gamma-bisabolene and the additional minor products E-nerolidol and alpha-bisabolol. Expressed in cortex and sub-epidermal layers of roots, leaf hydathodes and flower stigmata. Induced by wounding.
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    Genomic context

    See TPS12 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (7733114..7736745, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene cytochrome P450, family 71, subfamily A, polypeptide 19 Neighboring gene terpenoid synthase 13

    Pathways from PubChem

    General gene information

    NM_001340846.1
    NM_117401.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables (Z)-gamma-bisabolene synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables cyclase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables terpene synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    terpenoid synthase 12
    NP_193064.2
    • terpenoid synthase 12 (TPS12); FUNCTIONS IN: cyclase activity; INVOLVED IN: response to wounding, sesquiterpenoid biosynthetic process, farnesyl diphosphate metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: root cortex, stigma, hydathode; CONTAINS InterPro DOMAIN/s: Terpene synthase, metal-binding domain (InterPro:IPR005630), Terpenoid synthase (InterPro:IPR008949), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Terpene synthase-like (InterPro:IPR001906); BEST Arabidopsis thaliana protein match is: terpenoid synthase 13 (TAIR:AT4G13300.1); Has 1634 Blast hits to 1617 proteins in 174 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1630; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      7733114..7736745 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117401.2NP_193064.2  terpenoid synthase 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193064.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FNT7
      Conserved Domains (1) summary
      cd00684
      Location:22521
      Terpene_cyclase_plant_C1; Plant Terpene Cyclases, Class 1
    2. NM_001340846.1NP_001328007.1  terpenoid synthase 12 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JSZ6, Q9T0J9
      UniProtKB/TrEMBL
      A0A654FNT7