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    MPB2C movement protein binding protein 2C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830707, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MPB2C
    Official Full Name
    movement protein binding protein 2C
    Primary source
    TAIR:AT5G08120
    Locus tag
    AT5G08120
    See related
    Araport:AT5G08120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMBP2C; MBP2C; MICROTUBULE BINDING PROTEIN 2C; movement protein binding protein 2C
    Summary
    Microtubule-associated and viral movement protein binding protein. Negatively regulates KN1 association to plasmodesmata and, consequently, cell-to-cell transport. Involved in the alignment of cortical microtubules, the patterning of stomata and in restricting tobamoviral infections.
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    Genomic context

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    See MPB2C in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (2600443..2602935, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein Neighboring gene UBQ, helicase-c and DEAD-like helicase domain-containing protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microtubule-associated protein AtMPB2C plays a role in organization of cortical microtubules, stomata patterning, and tobamovirus infectivity. Ruggenthaler P, et al. Plant Physiol, 2009 Mar. PMID 19074626, Free PMC Article
    2. MPB2C, a microtubule-associated protein, regulates non-cell-autonomy of the homeodomain protein KNOTTED1. Winter N, et al. Plant Cell, 2007 Oct. PMID 17965274, Free PMC Article
    3. Identification of plant cytoskeletal, cell cycle-related and polarity-related proteins using Schizosaccharomyces pombe. Xia G, et al. Plant J, 1996 Oct. PMID 8893552
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtMPB2C is involved in the alignment of cortical microtubules, the patterning of stomata, and restricting tobamoviral infections. [AtMPB2C]
      Title: Microtubule-associated protein AtMPB2C plays a role in organization of cortical microtubules, stomata patterning, and tobamovirus infectivity.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001342982.1
    NM_120894.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cortical microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to virus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of protein transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in plasmodesmata-mediated intercellular transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within plasmodesmata-mediated intercellular transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of defense response to virus by host IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cytoskeleton organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal complex patterning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    movement protein binding protein 2C
    NP_196429.1
    • movement protein binding protein 2C (MPB2C); Has 5726 Blast hits to 4344 proteins in 670 species: Archae - 77; Bacteria - 646; Metazoa - 3260; Fungi - 443; Plants - 256; Viruses - 12; Other Eukaryotes - 1032 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2600443..2602935 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120894.5 → NP_196429.1  movement protein binding protein 2C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196429.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1P8BFS6, P92987, Q9LEZ4
      UniProtKB/TrEMBL
      A0A178UL06, A0A5S9Y4L8, A0A7G2F6F3
      Conserved Domains (1) summary
      COG1196
      Location:90 → 252
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. NM_001342982.1 → NP_001332071.1  movement protein binding protein 2C [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2F6F3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LEZ4.1

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