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    UBP22 ubiquitin-specific protease 22 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830946, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBP22
    Official Full Name
    ubiquitin-specific protease 22
    Primary source
    TAIR:AT5G10790
    Locus tag
    AT5G10790
    See related
    Araport:AT5G10790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T30N20.60; T30N20_60; ubiquitin-specific protease 22; UBIQUITIN-SPECIFIC PROTEASE 22
    Summary
    Encodes a ubiquitin-specific protease.
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    Genomic context

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    See UBP22 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (3410085..3413036)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene ER membrane protein complex subunit-like protein Neighboring gene RNA recognition motif (RRM)-containing protein Neighboring gene enhancer of rudimentary protein Neighboring gene Major facilitator superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis. Nassrallah A, et al. Elife, 2018 Sep 7. PMID 30192741, Free PMC Article
    2. The Adaptor Protein ENY2 Is a Component of the Deubiquitination Module of the Arabidopsis SAGA Transcriptional Co-activator Complex but not of the TREX-2 Complex. Pfab A, et al. J Mol Biol, 2018 May 11. PMID 29588169
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis
      Title: DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_121117.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of SAGA-type complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-specific protease 22
    NP_568239.1
    • ubiquitin-specific protease 22 (UBP22); FUNCTIONS IN: ubiquitin-specific protease activity, ubiquitin thiolesterase activity, zinc ion binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, UBP-type (InterPro:IPR001607), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 23 (TAIR:AT5G57990.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3410085..3413036
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343137.1 → NP_001332186.1  ubiquitin-specific protease 22 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BG54

    2. NM_121117.2 → NP_568239.1  ubiquitin-specific protease 22 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568239.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FPS5, Q9LEW0
      UniProtKB/TrEMBL
      A0A178UPE9, A0A5S9Y3P0
      Conserved Domains (2) summary
      cd02660
      Location:177 → 528
      Peptidase_C19D; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam02148
      Location:56 → 116
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LEW0.1

    Gene LinkOut

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