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    PIR121 transcription activator [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831959, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIR121
    Official Full Name
    transcription activator
    Primary source
    TAIR:AT5G18410
    Locus tag
    AT5G18410
    See related
    Araport:AT5G18410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSRA1; F20L16.130; F20L16_130; KLK; KLUNKER; PIR; PIROGI; PIROGI 121; PIRP; SRA1
    Summary
    distorted trichomes and exhibits a diffuse actin cytoskeleton
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    Genomic context

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    See PIR121 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    31
    Sequence:
    Chromosome: 5; NC_003076.8 (6096945..6105104, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Putative membrane lipoprotein Neighboring gene uncharacterized protein Neighboring gene Defensin-like (DEFL) family protein Neighboring gene CCR4-NOT transcription complex subunit Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis NAP and PIR regulate actin-based cell morphogenesis and multiple developmental processes. Li Y, et al. Plant Physiol, 2004 Nov. PMID 15516496, Free PMC Article
    2. Arabidopsis NAP1 is essential for Arp2/3-dependent trichome morphogenesis. Deeks MJ, et al. Curr Biol, 2004 Aug 10. PMID 15296761
    3. Arabidopsis GNARLED encodes a NAP125 homolog that positively regulates ARP2/3. El-Assal Sel-D, et al. Curr Biol, 2004 Aug 10. PMID 15296760
    4. Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development. Basu D, et al. Development, 2004 Sep. PMID 15294869
    5. The actin cytoskeleton is required to elaborate and maintain spatial patterning during trichome cell morphogenesis in Arabidopsis thaliana. Mathur J, et al. Development, 1999 Dec. PMID 10572033

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001125776.1
    NM_121846.4
    NM_203072.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within actin nucleation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within trichome morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCAR complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    transcription activator
    NP_001119248.1
    • PIROGI 121 (PIR121); FUNCTIONS IN: transcription activator activity; INVOLVED IN: actin nucleation, trichome morphogenesis, actin cytoskeleton organization; LOCATED IN: SCAR complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytoplasmic FMR1-interacting (InterPro:IPR008081); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_197342.3
    • PIROGI 121 (PIR121); CONTAINS InterPro DOMAIN/s: Cytoplasmic FMR1-interacting (InterPro:IPR008081), Cytoplasmic FMR1-interacting, subgroup (InterPro:IPR016536); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_974801.2
    • PIROGI 121 (PIR121); CONTAINS InterPro DOMAIN/s: Cytoplasmic FMR1-interacting (InterPro:IPR008081), Cytoplasmic FMR1-interacting, subgroup (InterPro:IPR016536); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6096945..6105104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_203072.3 → NP_974801.2  transcription activator [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974801.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E9F2, Q5S2C3, Q6DLU3
      UniProtKB/TrEMBL
      A0A178UQQ9, A0A654G2A8
      Conserved Domains (1) summary
      PLN03099
      Location:1 → 1278
      PIR; Protein PIR; Provisional

    2. NM_121846.4 → NP_197342.3  transcription activator [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197342.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G2A8
      Conserved Domains (1) summary
      PLN03099
      Location:1 → 1279
      PIR; Protein PIR; Provisional

    3. NM_001125776.1 → NP_001119248.1  transcription activator [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119248.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H6L9
      Conserved Domains (1) summary
      PLN03099
      Location:1 → 1021
      PIR; Protein PIR; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5S2C3.2

    Gene LinkOut

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