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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831953, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT5G18350
    Locus tag
    AT5G18350
    See related
    Araport:AT5G18350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20L16.70; F20L16_70
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (6074069..6078615, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ARM repeat superfamily protein Neighboring gene ARM repeat superfamily protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene disease resistance protein (TIR-NBS-LRR class) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_121840.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_197336.4
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G18370.1); Has 34965 Blast hits to 21666 proteins in 724 species: Archae - 44; Bacteria - 2561; Metazoa - 2994; Fungi - 173; Plants - 27913; Viruses - 8; Other Eukaryotes - 1272 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6074069..6078615 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121840.5 → NP_197336.4  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197336.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G244, F4JWL7
      Conserved Domains (6) summary
      cd09293
      Location:661 → 761
      AMN1; Antagonist of mitotic exit network protein 1
      PLN03210
      Location:6 → 1173
      PLN03210; Resistant to P. syringae 6; Provisional
      cd00116
      Location:591 → 723
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:624 → 646
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:20 → 183
      TIR; TIR domain
      pfam13191
      Location:194 → 329
      AAA_16; AAA ATPase domain
    Nucleotide Protein
    Heading Accession and Version

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