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    PGL5 6-phosphogluconolactonase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832513, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PGL5
    Official Full Name
    6-phosphogluconolactonase 5
    Primary source
    TAIR:AT5G24420
    Locus tag
    AT5G24420
    See related
    Araport:AT5G24420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    6-phosphogluconolactonase 5; K16H17.13; K16H17_13
    Summary
    Encodes a cytosolic 6-phosphogluconolactonase (PGL) thought to be involved in the oxidative pentose-phosphate pathway (OPPP).
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    Genomic context

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    See PGL5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (8336534..8338032, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene NagB/RpiA/CoA transferase-like superfamily protein Neighboring gene 6-phosphogluconolactonase 4 Neighboring gene Calcium-dependent protein kinase (CDPK) family protein Neighboring gene CTC-interacting domain 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of potential redundancy among Arabidopsis 6-phosphogluconolactonase isoforms in peroxisomes. Lansing H, et al. J Exp Bot, 2020 Jan 23. PMID 31641750
    2. Dual-targeting of Arabidopsis 6-phosphogluconolactonase 3 (PGL3) to chloroplasts and peroxisomes involves interaction with Trx m2 in the cytosol. Hölscher C, et al. Mol Plant, 2014 Jan. PMID 24008768
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Analysis of potential redundancy among Arabidopsis 6-phosphogluconolactonase isoforms in peroxisomes.
      Title: Analysis of potential redundancy among Arabidopsis 6-phosphogluconolactonase isoforms in peroxisomes.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_122350.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 6-phosphogluconolactonase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pentose-phosphate shunt IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    6-phosphogluconolactonase 5
    NP_197830.1
    • 6-phosphogluconolactonase 5 (PGL5); FUNCTIONS IN: 6-phosphogluconolactonase activity; INVOLVED IN: pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch, carbohydrate metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: 6-phosphogluconolactonase, DevB-type (InterPro:IPR005900); BEST Arabidopsis thaliana protein match is: 6-phosphogluconolactonase 2 (TAIR:AT3G49360.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8336534..8338032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122350.4 → NP_197830.1  6-phosphogluconolactonase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197830.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LEV7, Q9FIN0
      UniProtKB/TrEMBL
      A0A5S9Y6W9, A0A654G3Q4
      Conserved Domains (1) summary
      cl00339
      Location:8 → 252
      SugarP_isomerase; SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LEV7.2

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