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    WR3 nitrate transmembrane transporter [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835085, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WR3
    Official Full Name
    nitrate transmembrane transporter
    Primary source
    TAIR:AT5G50200
    Locus tag
    AT5G50200
    See related
    Araport:AT5G50200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNRT3.1; K6A12.6; K6A12_6; NITRATE TRANSPORTER 3.1; NRT3.1; WOUND-RESPONSIVE 3
    Summary
    Wound-responsive gene 3 (WR3). Encodes a high-affinity nitrate transporter. Up-regulated by nitrate. Involved in jasmonic acid-independent wound signal transduction.
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    Genomic context

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    See WR3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (20436180..20437815)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene ncRNA Neighboring gene quinolinate synthase Neighboring gene F-box family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A 150 kDa plasma membrane complex of AtNRT2.5 and AtNAR2.1 is the major contributor to constitutive high-affinity nitrate influx in Arabidopsis thaliana. Kotur Z, et al. Plant Cell Environ, 2015 Aug. PMID 25474587
    2. Characterization of an intact two-component high-affinity nitrate transporter from Arabidopsis roots. Yong Z, et al. Plant J, 2010 Sep. PMID 20561257
    3. Characterization of a two-component high-affinity nitrate uptake system in Arabidopsis. Physiology and protein-protein interaction. Orsel M, et al. Plant Physiol, 2006 Nov. PMID 17012411, Free PMC Article
    4. High-affinity nitrate transport in roots of Arabidopsis depends on expression of the NAR2-like gene AtNRT3.1. Okamoto M, et al. Plant Physiol, 2006 Mar. PMID 16415212, Free PMC Article
    5. Regulation of the high-affinity NO3- uptake system by NRT1.1-mediated NO3- demand signaling in Arabidopsis. Krouk G, et al. Plant Physiol, 2006 Nov. PMID 16998085, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtNRT2.5 is predominantly expressed in roots of nitrate-deprived WT plants as a 150 kDa molecular complex with AtNAR2.1 which is the major contributor to constitutive high-affinity nitrate influx in Arabidopsis thaliana. [NAR2.1]
      Title: A 150 kDa plasma membrane complex of AtNRT2.5 and AtNAR2.1 is the major contributor to constitutive high-affinity nitrate influx in Arabidopsis thaliana.
    2. Except for AtNRT2.7, all other NRT2 transporters interact strongly with AtNAR2.1.
      Title: Nitrate transport capacity of the Arabidopsis thaliana NRT2 family members and their interactions with AtNAR2.1.
    3. Data demonstrate that an intact two-component complex of AtNRT2.1 and AtNAR2.1 (AtNRT3.1) is localized in the plasma membrane.
      Title: Characterization of an intact two-component high-affinity nitrate transporter from Arabidopsis roots.
    4. AtNAR2.1 is essential for high-affinity transport system of nitrate in Arabidopsis.[NAR2.1]
      Title: Characterization of a two-component high-affinity nitrate uptake system in Arabidopsis. Physiology and protein-protein interaction.
    5. The NRT3.1 gene encodes a key component of the HATS (high-affinity NO3 transport system) and repression of NRT2.1 and NRT3.1 by high nitrates is specifically mediated by the NRT1.1 transporter. [NRT3.1]
      Title: Regulation of the high-affinity NO3- uptake system by NRT1.1-mediated NO3- demand signaling in Arabidopsis.
    6. The constitutive high-affinity influx and nitrate-inducible high-affinity influx (but not the low-affinity influx) of higher plant roots require a functional AtNRT3 gene. [AtNRT3.1]
      Title: High-affinity nitrate transport in roots of Arabidopsis depends on expression of the NAR2-like gene AtNRT3.1.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_124399.3
    NM_180828.2
    NM_180829.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nitrate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within nitrate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nitrate IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    nitrate transmembrane transporter
    NP_199831.1
    • WOUND-RESPONSIVE 3 (WR3); FUNCTIONS IN: nitrate transmembrane transporter activity; INVOLVED IN: nitrate transport, response to nitrate, response to wounding; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Transporter, high affinity nitrate, Nar2 (InterPro:IPR016605); BEST Arabidopsis thaliana protein match is: Calcineurin-like metallo-phosphoesterase superfamily protein (TAIR:AT4G24730.4); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_851159.1
    • WOUND-RESPONSIVE 3 (WR3); FUNCTIONS IN: nitrate transmembrane transporter activity; INVOLVED IN: nitrate transport, response to nitrate, response to wounding; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Transporter, high affinity nitrate, Nar2 (InterPro:IPR016605); BEST Arabidopsis thaliana protein match is: Calcineurin-like metallo-phosphoesterase superfamily protein (TAIR:AT4G24730.4); Has 71 Blast hits to 71 proteins in 18 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 71; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).
    NP_851160.1
    • WOUND-RESPONSIVE 3 (WR3); FUNCTIONS IN: nitrate transmembrane transporter activity; INVOLVED IN: nitrate transport, response to nitrate, response to wounding; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Transporter, high affinity nitrate, Nar2 (InterPro:IPR016605); BEST Arabidopsis thaliana protein match is: Calcineurin-like metallo-phosphoesterase superfamily protein (TAIR:AT4G24730.4); Has 71 Blast hits to 71 proteins in 18 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 71; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20436180..20437815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124399.3 → NP_199831.1  nitrate transmembrane transporter [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199831.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LE73, Q9ARM2, Q9FGS5
      UniProtKB/TrEMBL
      A0A178UEV0, A0A5S9YCQ1, A0A654G9P1
      Conserved Domains (1) summary
      pfam16974
      Location:29 → 204
      NAR2; High-affinity nitrate transporter accessory

    2. NM_180829.1 → NP_851160.1  nitrate transmembrane transporter [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851160.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LE73, Q9ARM2, Q9FGS5
      UniProtKB/TrEMBL
      A0A178UEV0, A0A5S9YCQ1, A0A654G9P1
      Conserved Domains (1) summary
      pfam16974
      Location:29 → 204
      NAR2; High-affinity nitrate transporter accessory

    3. NM_180828.2 → NP_851159.1  nitrate transmembrane transporter [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851159.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LE73, Q9ARM2, Q9FGS5
      UniProtKB/TrEMBL
      A0A178UEV0, A0A5S9YCQ1, A0A654G9P1
      Conserved Domains (1) summary
      pfam16974
      Location:29 → 204
      NAR2; High-affinity nitrate transporter accessory
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FGS5.1

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