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    DPE1 disproportionating enzyme [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836609, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DPE1
    Official Full Name
    disproportionating enzyme
    Primary source
    TAIR:AT5G64860
    Locus tag
    AT5G64860
    See related
    Araport:AT5G64860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    disproportionating enzyme; MXK3.9; MXK3_9
    Summary
    Encodes a maltotriose-metabolizing enzyme with chloroplastic alpha-1,4-glucanotransferase activity. Mutant has altered starch degradation.
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    Genomic context

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    See DPE1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (25925173..25928879, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene tRNA-Leu Neighboring gene SPFH/Band 7/PHB domain-containing membrane-associated protein family Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1). O'Neill EC, et al. J Biol Chem, 2015 Dec 11. PMID 26504082, Free PMC Article
    2. Blocking the metabolism of starch breakdown products in Arabidopsis leaves triggers chloroplast degradation. Stettler M, et al. Mol Plant, 2009 Nov. PMID 19946617, Free PMC Article
    3. A critical role for disproportionating enzyme in starch breakdown is revealed by a knock-out mutation in Arabidopsis. Critchley JH, et al. Plant J, 2001 Apr. PMID 11359613
    4. Mutations in leaf starch metabolism modulate the diurnal root growth profiles of Arabidopsis thaliana. Yazdanbakhsh N, et al. Plant Signal Behav, 2011 Jul. PMID 21691153, Free PMC Article
    5. Starch degradation. Smith AM, et al. Annu Rev Plant Biol, 2005. PMID 15862090

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtDPE1 forms a homodimer with a deep, long, and open-ended active site canyon contained within each subunit
      Title: Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1).
    2. pgm, sex1, mex1, dpe1 and dpe2 starch metabolism mutants grown in three different photoperiods display root growth patterns of all genotypes characteristic modifications in their diurnal kinetics that were also affected by the photoperiod.
      Title: Mutations in leaf starch metabolism modulate the diurnal root growth profiles of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_125884.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4-alpha-glucanotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 4-alpha-glucanotransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within glucose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maltose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within starch catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in starch catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within starch catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    disproportionating enzyme
    NP_201291.1
    • disproportionating enzyme (DPE1); FUNCTIONS IN: 4-alpha-glucanotransferase activity, cation binding, catalytic activity; INVOLVED IN: response to cold, starch catabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 77 (InterPro:IPR003385), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: disproportionating enzyme 2 (TAIR:AT2G40840.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25925173..25928879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125884.4 → NP_201291.1  disproportionating enzyme [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201291.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LV91
      UniProtKB/TrEMBL
      A0A178U766, A0A5S9YH17, A0A654GE62
      Conserved Domains (1) summary
      PLN02635
      Location:56 → 576
      PLN02635; disproportionating enzyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LV91.1

    Gene LinkOut

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