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    HIPP21 Heavy metal transport/detoxification superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831611, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HIPP21
    Official Full Name
    Heavy metal transport/detoxification superfamily protein
    Primary source
    TAIR:AT5G17450
    Locus tag
    AT5G17450
    See related
    Araport:AT5G17450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    heavy metal associated isoprenylated plant protein 21; K3M16.20; K3M16_20
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    Genomic context

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    See HIPP21 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (5755222..5757003)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene LUC7 related protein Neighboring gene ncRNA Neighboring gene glutamyl-tRNA (Gln) amidotransferase subunit C Neighboring gene EF hand calcium-binding protein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Metallochaperone-like genes in Arabidopsis thaliana. Tehseen M, et al. Metallomics, 2010 Aug. PMID 21072340
    2. Identification of a functional homolog of the yeast copper homeostasis gene ATX1 from Arabidopsis. Himelblau E, et al. Plant Physiol, 1998 Aug. PMID 9701579, Free PMC Article
    3. Stress induced and nuclear localized HIPP26 from Arabidopsis thaliana interacts via its heavy metal associated domain with the drought stress related zinc finger transcription factor ATHB29. Barth O, et al. Plant Mol Biol, 2009 Jan. PMID 18974936
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121751.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in detoxification of cadmium ion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within metal ion transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Heavy metal transport/detoxification superfamily protein
    NP_001318583.1
    • Heavy metal transport/detoxification superfamily protein; FUNCTIONS IN: metal ion binding; INVOLVED IN: metal ion transport; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121); BEST Arabidopsis thaliana protein match is: Heavy metal transport/detoxification superfamily protein (TAIR:AT1G71050.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_197247.1
    • Heavy metal transport/detoxification superfamily protein; FUNCTIONS IN: metal ion binding; INVOLVED IN: metal ion transport; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121); BEST Arabidopsis thaliana protein match is: Heavy metal transport/detoxification superfamily protein (TAIR:AT1G71050.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5755222..5757003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343499.1 → NP_001318583.1  Heavy metal transport/detoxification superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UM46, Q3E9G4
      Conserved Domains (1) summary
      cd00371
      Location:8 → 44
      HMA; Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...

    2. NM_121751.3 → NP_197247.1  Heavy metal transport/detoxification superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197247.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LF57
      UniProtKB/TrEMBL
      A0A5S9Y5J0, A0A654G2A9
      Conserved Domains (1) summary
      cd00371
      Location:29 → 88
      HMA; Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LF57.1

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