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    CPN20 chaperonin 20 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832195, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CPN20
    Official Full Name
    chaperonin 20
    Primary source
    TAIR:AT5G20720
    Locus tag
    AT5G20720
    See related
    Araport:AT5G20720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCPN21; CHAPERONIN 10; chaperonin 20; CHCPN10; CHLOROPLAST CHAPERONIN 10; CPN10; CPN21; T1M15.120; T1M15_120
    Summary
    Encodes a chloroplast co-chaperonin with similarity to CPN21 from spinach, E.coli GroES.
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    Genomic context

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    See CPN20 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (7014662..7016698)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene senescence-associated family protein, putative (DUF581) Neighboring gene beta-galactosidase 7 Neighboring gene ncRNA Neighboring gene Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein Neighboring gene ncRNA Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. cDNA sequence and overexpression of chloroplast chaperonin 21 from Arabidopsis thaliana. Hirohashi T, et al. Biochim Biophys Acta, 1999 Jan 11. PMID 9989238
    2. Chloroplast Cpn20 forms a tetrameric structure in Arabidopsis thaliana. Koumoto Y, et al. Plant J, 1999 Mar. PMID 10205903
    3. O-fucosylation of CPN20 by SPINDLY Derepresses Abscisic Acid Signaling During Seed Germination and Seedling Development. Liang L, et al. Front Plant Sci, 2021. PMID 34712252, Free PMC Article
    4. The Cpn10(1) co-chaperonin of A. thaliana functions only as a hetero-oligomer with Cpn20. Vitlin Gruber A, et al. PLoS One, 2014. PMID 25419702, Free PMC Article
    5. Arabidopsis co-chaperonin CPN20 antagonizes Mg-chelatase H subunit to derepress ABA-responsive WRKY40 transcription repressor. Zhang X, et al. Sci China Life Sci, 2014 Jan. PMID 24369350

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that chaperonin Cpn10(1) (At3g60210) is active only upon formation of hetero-oligomers with chaperonin Cpn20 (At5g20720).
      Title: The Cpn10(1) co-chaperonin of A. thaliana functions only as a hetero-oligomer with Cpn20.
    2. provide evidence that CPN20 functions through antagonizing the ABAR-WRKY40 coupled pathway, and ABA relieves this pathway of repression by inhibiting the ABAR-CPN20 interaction to activate ABAR-WRKY40 interaction
      Title: Arabidopsis co-chaperonin CPN20 antagonizes Mg-chelatase H subunit to derepress ABA-responsive WRKY40 transcription repressor.
    3. findings show that CPN20 functions negatively in the ABAR-WRKY40 coupled ABA signaling independently of its co-chaperonin role, and provide a new insight into the role of co-chaperones in the regulation of plant responses to environmental cues.
      Title: Cochaperonin CPN20 negatively regulates abscisic acid signaling in Arabidopsis.
    4. CPN20 silencing decreases iron superoxide dismutases activity in chloroplast.
      Title: CHAPERONIN 20 mediates iron superoxide dismutase (FeSOD) activity independent of its co-chaperonin role in Arabidopsis chloroplasts.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001343684.1
    NM_001343685.1
    NM_122079.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables copper ion binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables superoxide dismutase copper chaperone activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein heterotetramerization IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast thylakoid membrane HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plastid HDA PubMed 
    located_in thylakoid HDA PubMed 

    General protein information

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    Preferred Names
    chaperonin 20
    NP_001318614.1
    • chaperonin 20 (CPN20); CONTAINS InterPro DOMAIN/s: Chaperonin Cpn10 (InterPro:IPR020818), GroES-like (InterPro:IPR011032), Chaperonin Cpn10, conserved site (InterPro:IPR018369), Chaperonin 21, chloroplast (InterPro:IPR017416), Chaperonin Cpn10, subgroup (InterPro:IPR001476); BEST Arabidopsis thaliana protein match is: chaperonin 10 (TAIR:AT1G14980.1).
    NP_197572.1
    • chaperonin 20 (CPN20); FUNCTIONS IN: calmodulin binding, copper ion binding; INVOLVED IN: response to cadmium ion, response to cold; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn10 (InterPro:IPR020818), GroES-like (InterPro:IPR011032), Chaperonin Cpn10, conserved site (InterPro:IPR018369), Chaperonin 21, chloroplast (InterPro:IPR017416), Chaperonin Cpn10, subgroup (InterPro:IPR001476); BEST Arabidopsis thaliana protein match is: chaperonin 10 (TAIR:AT1G14980.1); Has 18503 Blast hits to 9472 proteins in 2912 species: Archae - 42; Bacteria - 12669; Metazoa - 631; Fungi - 230; Plants - 426; Viruses - 4; Other Eukaryotes - 4501 (source: NCBI BLink).
    NP_851045.1
    • chaperonin 20 (CPN20); FUNCTIONS IN: calmodulin binding, copper ion binding; INVOLVED IN: response to cadmium ion, response to cold; LOCATED IN: in 7 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn10 (InterPro:IPR020818), GroES-like (InterPro:IPR011032), Chaperonin Cpn10, conserved site (InterPro:IPR018369), Chaperonin 21, chloroplast (InterPro:IPR017416), Chaperonin Cpn10, subgroup (InterPro:IPR001476); BEST Arabidopsis thaliana protein match is: chaperonin 10 (TAIR:AT1G14980.1); Has 18503 Blast hits to 9472 proteins in 2912 species: Archae - 42; Bacteria - 12669; Metazoa - 631; Fungi - 230; Plants - 426; Viruses - 4; Other Eukaryotes - 4501 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7014662..7016698
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180714.4 → NP_851045.1  chaperonin 20 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851045.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65282, Q9TNN2
      UniProtKB/TrEMBL
      A0A178UDQ4, A0A5S9Y5Z1
      Conserved Domains (1) summary
      PRK00364
      Location:61 → 153
      groES; co-chaperonin GroES; Reviewed

    2. NM_001343684.1 → NP_001318614.1  chaperonin 20 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65282, Q9TNN2
      UniProtKB/TrEMBL
      A0A178UDQ4, A0A5S9Y5Z1
      Conserved Domains (1) summary
      PRK00364
      Location:61 → 153
      groES; co-chaperonin GroES; Reviewed

    3. NM_122079.4 → NP_197572.1  chaperonin 20 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197572.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65282, Q9TNN2
      UniProtKB/TrEMBL
      A0A178UDQ4, A0A5S9Y5Z1
      Conserved Domains (1) summary
      PRK00364
      Location:61 → 153
      groES; co-chaperonin GroES; Reviewed

    4. NM_001343685.1 → NP_001331898.1  chaperonin 20 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65282, Q9TNN2
      UniProtKB/TrEMBL
      A0A178UDQ4, A0A5S9Y5Z1
      Conserved Domains (1) summary
      PRK00364
      Location:61 → 153
      groES; co-chaperonin GroES; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O65282.2

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