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    CXIP2 CAX-interacting protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818407, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CXIP2
    Official Full Name
    CAX-interacting protein 2
    Primary source
    TAIR:AT2G38270
    Locus tag
    AT2G38270
    See related
    Araport:AT2G38270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGRX2; AtGRXS16; CAX-interacting protein 2; F16M14.20; F16M14_20; GLUTAREDOXIN; glutaredoxin 16; GLUTAREDOXIN 2
    Summary
    Encodes protein homologous to CXIP1. CXIP1 is a PICOT domain containing protein interacts with CAX1, a high capacity calcium transporter. However, CXP2 does not interact with CAX1 and only moderately activates another calcium transporter CAX4.
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    Genomic context

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    See CXIP2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (16031185..16033169, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF239) Neighboring gene miscRNA Neighboring gene AMP deaminase, putative / myoadenylate deaminase Neighboring gene ammonium transporter 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The thioredoxin-mediated recycling of Arabidopsis thaliana GRXS16 relies on a conserved C-terminal cysteine. Zannini F, et al. Biochim Biophys Acta Gen Subj, 2019 Feb. PMID 30502392
    2. Involvement of Arabidopsis glutaredoxin S14 in the maintenance of chlorophyll content. Rey P, et al. Plant Cell Environ, 2017 Oct. PMID 28741719
    3. Cloning and characterization of CXIP1, a novel PICOT domain-containing Arabidopsis protein that associates with CAX1. Cheng NH, et al. J Biol Chem, 2003 Feb 21. PMID 12480930
    4. Monothiol glutaredoxin-BolA interactions: redox control of Arabidopsis thaliana BolA2 and SufE1. Couturier J, et al. Mol Plant, 2014 Jan. PMID 24203231
    5. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129383.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic cation transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 

    General protein information

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    Preferred Names
    CAX-interacting protein 2
    NP_565885.1
    • CAX-interacting protein 2 (CXIP2); FUNCTIONS IN: electron carrier activity, protein disulfide oxidoreductase activity; INVOLVED IN: cation transport; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Glutaredoxin (InterPro:IPR002109), Thioredoxin-like fold (InterPro:IPR012336), Glutaredoxin-related protein (InterPro:IPR004480); BEST Arabidopsis thaliana protein match is: CAX interacting protein 1 (TAIR:AT3G54900.1); Has 5833 Blast hits to 5648 proteins in 1292 species: Archae - 30; Bacteria - 2544; Metazoa - 528; Fungi - 278; Plants - 476; Viruses - 0; Other Eukaryotes - 1977 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16031185..16033169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129383.3 → NP_565885.1  CAX-interacting protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565885.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80451, Q8H7F6, Q8LD13
      UniProtKB/TrEMBL
      A0A178VW24, A0A5S9X547, A0A7G2ECH3
      Conserved Domains (2) summary
      cd10457
      Location:88 → 161
      GIY-YIG_AtGrxS16; GIY-YIG domain found in CAXIP1-like proteins
      cd03028
      Location:197 → 289
      GRX_PICOT_like; Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H7F6.2

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