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    RPA root and pollen arfgap [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818088, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPA
    Official Full Name
    root and pollen arfgap
    Primary source
    TAIR:AT2G35210
    Locus tag
    AT2G35210
    See related
    Araport:AT2G35210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AGD10; MATERNAL EFFECT EMBRYO ARREST 28; MEE28; root and pollen arfgap; T4C15.12; T4C15_12
    Summary
    A member of ARF GAP domain (AGD), A thaliana has 15 members, grouped into four classes.
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    Genomic context

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    See RPA in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (14836062..14838151)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene DUF740 family protein Neighboring gene ncRNA Neighboring gene plant/protein Neighboring gene ncRNA Neighboring gene tRNA-Met

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Replication protein A (AtRPA1a) is required for class I crossover formation but is dispensable for meiotic DNA break repair. Osman K, et al. EMBO J, 2009 Feb 18. PMID 19153602, Free PMC Article
    2. RPA, a class II ARFGAP protein, activates ARF1 and U5 and plays a role in root hair development in Arabidopsis. Song XF, et al. Plant Physiol, 2006 Jul. PMID 16731582, Free PMC Article
    3. IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis. Liu M, et al. Plant Cell, 2017 Mar. PMID 28223440, Free PMC Article
    4. A collection of Ds insertional mutants associated with defects in male gametophyte development and function in Arabidopsis thaliana. Boavida LC, et al. Genetics, 2009 Apr. PMID 19237690, Free PMC Article
    5. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The findings support a model in which IDN2 interacts with RPA and facilitates the release of RPA from single-stranded DNA tails and subsequent recruitment of RAD51 at DSB sites to promote DSB repair.
      Title: IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis.
    2. AtRPA1a is required for class I crossover formation but is dispensable for meiotic DNA break repair
      Title: Replication protein A (AtRPA1a) is required for class I crossover formation but is dispensable for meiotic DNA break repair.
    3. plays a role in root hair and pollen tube growth, most likely through the regulation of Arabidopsis ARF1 and ARF1-like protein U5 activity
      Title: RPA, a class II ARFGAP protein, activates ARF1 and U5 and plays a role in root hair development in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_129074.3
    NM_201874.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    root and pollen arfgap
    NP_565801.1
    • root and pollen arfgap (RPA); FUNCTIONS IN: ARF GTPase activator activity, DNA binding, zinc ion binding; INVOLVED IN: embryo development ending in seed dormancy, pollen development; LOCATED IN: nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 9 (TAIR:AT5G46750.1); Has 3638 Blast hits to 3466 proteins in 238 species: Archae - 0; Bacteria - 14; Metazoa - 1949; Fungi - 623; Plants - 559; Viruses - 0; Other Eukaryotes - 493 (source: NCBI BLink).
    NP_973603.1
    • root and pollen arfgap (RPA); FUNCTIONS IN: ARF GTPase activator activity, DNA binding, zinc ion binding; INVOLVED IN: embryo development ending in seed dormancy, pollen development; LOCATED IN: nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 9 (TAIR:AT5G46750.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14836062..14838151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129074.3 → NP_565801.1  root and pollen arfgap [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565801.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82171, Q3EBM9
      UniProtKB/TrEMBL
      A0A178VQN0, A0A5S9X431, A0A7G2EBF2
      Conserved Domains (1) summary
      PLN03114
      Location:1 → 395
      PLN03114; ADP-ribosylation factor GTPase-activating protein AGD10; Provisional

    2. NM_201874.2 → NP_973603.1  root and pollen arfgap [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973603.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EBF2
      Conserved Domains (2) summary
      PLN03114
      Location:1 → 370
      PLN03114; ADP-ribosylation factor GTPase-activating protein AGD10; Provisional
      pfam01412
      Location:12 → 122
      ArfGap; Putative GTPase activating protein for Arf
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82171.1

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