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    SNL3 SIN3-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839032, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SNL3
    Official Full Name
    SIN3-like 3
    Primary source
    TAIR:AT1G24190
    Locus tag
    AT1G24190
    See related
    Araport:AT1G24190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA SIN3 HOMOLOG; ATSIN3; F3I6.12; F3I6_12; SIN3; SIN3-like 3
    Summary
    Enhances AtERF7-mediated transcriptional repression. RNAi lines show ABA hypersensitivity. Interacts with ERF7 and HDA19.
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    Genomic context

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    See SNL3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    22
    Sequence:
    Chromosome: 1; NC_003070.9 (8563510..8570580, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Nucleotide-diphospho-sugar transferases superfamily protein Neighboring gene thiamine diphosphate-binding fold (THDP-binding) superfamily protein Neighboring gene Paired amphipathic helix (PAH2) superfamily protein Neighboring gene Paired amphipathic helix (PAH2) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses. Song CP, et al. Plant Cell, 2005 Aug. PMID 15994908, Free PMC Article
    2. Arabidopsis RPD3-like histone deacetylases form multiple complexes involved in stress response. Feng C, et al. J Genet Genomics, 2021 May 20. PMID 34144927
    3. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_102265.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Sin3-type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SIN3-like 3
    NP_001185080.1
    • SIN3-like 3 (SNL3); FUNCTIONS IN: transcription repressor activity; INVOLVED IN: negative regulation of transcription, regulation of transcription, DNA-dependent, response to abscisic acid stimulus; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone deacetylase interacting (InterPro:IPR013194), Paired amphipathic helix (InterPro:IPR003822); BEST Arabidopsis thaliana protein match is: SIN3-like 4 (TAIR:AT1G70060.1).
    NP_173829.3
    • SIN3-like 3 (SNL3); FUNCTIONS IN: transcription repressor activity; INVOLVED IN: negative regulation of transcription, regulation of transcription, DNA-dependent, response to abscisic acid stimulus; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone deacetylase interacting (InterPro:IPR013194), Paired amphipathic helix (InterPro:IPR003822); BEST Arabidopsis thaliana protein match is: SIN3-like 4 (TAIR:AT1G70060.1); Has 3268 Blast hits to 1788 proteins in 336 species: Archae - 19; Bacteria - 223; Metazoa - 1240; Fungi - 789; Plants - 447; Viruses - 29; Other Eukaryotes - 521 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8563510..8570580 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198151.2 → NP_001185080.1  SIN3-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185080.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9VUE0, F4I962
      Conserved Domains (4) summary
      smart00761
      Location:422 → 522
      HDAC_interact; Histone deacetylase (HDAC) interacting
      COG5602
      Location:10 → 767
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
      pfam02671
      Location:32 → 75
      PAH; Paired amphipathic helix repeat
      pfam16879
      Location:1049 → 1295
      Sin3a_C; C-terminal domain of Sin3a protein

    2. NM_001332641.1 → NP_001323398.1  SIN3-like 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AX02, A0A654END4

    3. NM_102265.3 → NP_173829.3  SIN3-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173829.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48686, Q0WTD6
      UniProtKB/TrEMBL
      A0A5S9VUE0
      Conserved Domains (4) summary
      smart00761
      Location:426 → 526
      HDAC_interact; Histone deacetylase (HDAC) interacting
      COG5602
      Location:10 → 771
      Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
      pfam02671
      Location:32 → 75
      PAH; Paired amphipathic helix repeat
      pfam16879
      Location:1053 → 1299
      Sin3a_C; C-terminal domain of Sin3a protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48686.3

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