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    MBF1A multiprotein bridging factor 1A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818868, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MBF1A
    Official Full Name
    multiprotein bridging factor 1A
    Primary source
    TAIR:AT2G42680
    Locus tag
    AT2G42680
    See related
    Araport:AT2G42680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA MULTIPROTEIN BRIDGING FACTOR 1A; ATMBF1A; F14N22.5; F14N22_5; multiprotein bridging factor 1A
    Summary
    One of three genes in A. thaliana encoding multiprotein bridging factor 1, a highly conserved transcriptional coactivator. May serve as a bridging factor between a bZIP factor and TBP. Its expression is developmentally regulated.
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    Genomic context

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    See MBF1A in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (17774832..17776320)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 2-aminoethanethiol dioxygenase, putative (DUF1637) Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene vesicle docking protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The analysis of an Arabidopsis triple knock-down mutant reveals functions for MBF1 genes under oxidative stress conditions. Arce DP, et al. J Plant Physiol, 2010 Feb 15. PMID 19783066
    2. Transcriptional coactivator MBF1s from Arabidopsis predominantly localize in nucleolus. Sugikawa Y, et al. J Plant Res, 2005 Dec. PMID 16283071
    3. Three Arabidopsis MBF1 homologs with distinct expression profiles play roles as transcriptional co-activators. Tsuda K, et al. Plant Cell Physiol, 2004 Feb. PMID 14988493
    4. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    5. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. triple knock-down mutant for MBF1a, MBF1b andtMBF1c sensitive to oxidative stress and osmotic stress
      Title: The analysis of an Arabidopsis triple knock-down mutant reveals functions for MBF1 genes under oxidative stress conditions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129829.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription coactivator activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    multiprotein bridging factor 1A
    NP_565981.1
    • multiprotein bridging factor 1A (MBF1A); CONTAINS InterPro DOMAIN/s: Lambda repressor-like, DNA-binding (InterPro:IPR010982), Multiprotein bridging factor 1, N-terminal (InterPro:IPR013729), Helix-turn-helix type 3 (InterPro:IPR001387); BEST Arabidopsis thaliana protein match is: multiprotein bridging factor 1B (TAIR:AT3G58680.1); Has 672 Blast hits to 672 proteins in 252 species: Archae - 42; Bacteria - 8; Metazoa - 193; Fungi - 147; Plants - 135; Viruses - 2; Other Eukaryotes - 145 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17774832..17776320
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129829.4 → NP_565981.1  multiprotein bridging factor 1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565981.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SJI8
      UniProtKB/TrEMBL
      A0A178VSD5, A0A5S9X6F7
      Conserved Domains (2) summary
      cl26727
      Location:85 → 141
      aMBF1; Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis]
      pfam08523
      Location:10 → 77
      MBF1; Multiprotein bridging factor 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJI8.1

    Gene LinkOut

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