GSTU24 glutathione S-transferase TAU 24 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: GSTU24
Official Full Name: glutathione S-transferase TAU 24
Primary source: TAIR:AT1G17170
Locus tag: AT1G17170
See related: Araport:AT1G17170
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: Arabidopsis thaliana Glutathione S-transferase (class tau) 24; ATGSTU24; F20D23.13; F20D23_13; glutathione S-transferase TAU 24; GST
Summary: Encodes glutathione transferase belonging to the tau class of GSTs. Naming convention according to Wagner et al. (2002).
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Genomic context

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See GSTU24 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 2

Sequence:: Chromosome: 1; NC_003070.9 (5869543..5870883)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

induced by 4.7-fold in response to 2,6-dinitrotoluene, but uptake rate and tolerance of mutant not significantly different
Title: Phytotoxicity and phytoremediation of 2,6-dinitrotoluene using a model plant, Arabidopsis thaliana.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_101578.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables glutathione binding	IDA Inferred from Direct Assay more info	PubMed
enables glutathione transferase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within 2,4,6-trinitrotoluene catabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within 2,4,6-trinitrotoluene catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glutathione metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within toxin catabolic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytoplasm	NAS Non-traceable Author Statement more info	PubMed
located_in cytosol	HDA more info	PubMed

General protein information

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Preferred Names: glutathione S-transferase TAU 24

NP_173160.1

glutathione S-transferase TAU 24 (GSTU24); FUNCTIONS IN: glutathione transferase activity, glutathione binding; INVOLVED IN: response to cyclopentenone, toxin catabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutathione S-transferase, C-terminal (InterPro:IPR004046), Glutathione S-transferase, C-terminal-like (InterPro:IPR010987), Glutathione S-transferase/chloride channel, C-terminal (InterPro:IPR017933), Glutathione S-transferase, N-terminal (InterPro:IPR004045), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: glutathione S-transferase TAU 25 (TAIR:AT1G17180.1); Has 6259 Blast hits to 6243 proteins in 1151 species: Archae - 0; Bacteria - 2699; Metazoa - 624; Fungi - 140; Plants - 2013; Viruses - 0; Other Eukaryotes - 783 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

5869543..5870883

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101578.3 → NP_173160.1 glutathione S-transferase TAU 24 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_173160.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9SHH6

UniProtKB/TrEMBL

A0A5S9UTQ3

Conserved Domains (3) summary

cd03185
Location:89 → 211

GST_C_Tau; C-terminal, alpha helical domain of Class Tau Glutathione S-transferases

COG0625
Location:6 → 197

GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]

cd03058
Location:5 → 78

GST_N_Tau; GST_N family, Class Tau subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...