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    HAI2 highly ABA-induced PP2C protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837255, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HAI2
    Official Full Name
    highly ABA-induced PP2C protein 2
    Primary source
    TAIR:AT1G07430
    Locus tag
    AT1G07430
    See related
    Araport:AT1G07430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AIP1; AKT1 interacting protein phosphatase 1; AtAIP1; F22G5.22; F22G5_22; highly ABA-induced PP2C gene 2; HON; HONSU (Korean for abnormal drowsiness)
    Summary
    Encodes a member of the group A protein phosphatase 2C (PP2C) family that is responsible for negatively regulating seed dormancy.
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    Genomic context

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    See HAI2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (2280746..2282828, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RAB GTPase homolog A2B Neighboring gene sterol 4-alpha-methyl-oxidase 2-1 Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HONSU, a protein phosphatase 2C, regulates seed dormancy by inhibiting ABA signaling in Arabidopsis. Kim W, et al. Plant Cell Physiol, 2013 Apr. PMID 23378449
    2. Functional roles of the protein phosphatase 2C, AtAIP1, in abscisic acid signaling and sugar tolerance in Arabidopsis. Lim CW, et al. Plant Sci, 2012 May. PMID 22404835
    3. Mechanistic analysis of AKT1 regulation by the CBL-CIPK-PP2CA interactions. Lan WZ, et al. Mol Plant, 2011 May. PMID 21596690
    4. Unique drought resistance functions of the highly ABA-induced clade A protein phosphatase 2Cs. Bhaskara GB, et al. Plant Physiol, 2012 Sep. PMID 22829320, Free PMC Article
    5. The unique mode of action of a divergent member of the ABA-receptor protein family in ABA and stress signaling. Zhao Y, et al. Cell Res, 2013 Dec. PMID 24189045, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_100617.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of seed dormancy process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of gibberellic acid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within release of seed from dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    highly ABA-induced PP2C protein 2
    NP_172223.1
    • highly ABA-induced PP2C gene 2 (HAI2); FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: protein amino acid dephosphorylation; LOCATED IN: protein serine/threonine phosphatase complex; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C, manganese/magnesium aspartate binding site (InterPro:IPR000222), Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: highly ABA-induced PP2C gene 3 (TAIR:AT2G29380.1); Has 6753 Blast hits to 6737 proteins in 407 species: Archae - 6; Bacteria - 193; Metazoa - 1700; Fungi - 794; Plants - 2782; Viruses - 7; Other Eukaryotes - 1271 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2280746..2282828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100617.3 → NP_172223.1  highly ABA-induced PP2C protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172223.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LFK5, Q9LNW3
      UniProtKB/TrEMBL
      A0A178W3W3, A0A5S9T3B3
      Conserved Domains (1) summary
      smart00332
      Location:116 → 431
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LNW3.1

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