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    LON4 lon protease 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819748, updated on 18-Sep-2024

    Summary

    Official Symbol
    LON4
    Official Full Name
    lon protease 4
    Primary source
    TAIR:AT3G05790
    Locus tag
    AT3G05790
    See related
    Araport:AT3G05790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10A16.8; F10A16_8; lon protease 4
    Summary
    Encodes a member of the Lon protease-like proteins (Lon1/At5g26860, Lon2/At5g47040, Lon3/At3g05780, Lon4/At3g05790). Lon is a multifunctional ATP-dependent protease which exists in bacteria, archaea and within organelles in eukaryotic cells. Lon proteases are responsible for the degradation of abnormal, damaged and unstable proteins.
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    Genomic context

    See LON4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    19
    Sequence:
    Chromosome: 3; NC_003074.8 (1719958..1725268, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene lon protease-like protein Neighboring gene lon protease 3 Neighboring gene AtBS1(activation-tagged BRI1 suppressor 1)-interacting factor 1 Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    NM_111453.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    lon protease 4
    NP_566259.1
    • lon protease 4 (LON4); FUNCTIONS IN: in 6 functions; INVOLVED IN: proteolysis; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), Peptidase S16, active site (InterPro:IPR008268), Peptidase S16, ATP-dependent protease La (InterPro:IPR004815), Peptidase S16, lon N-terminal (InterPro:IPR003111), Peptidase S16, Lon C-terminal (InterPro:IPR008269), ATPase, AAA+ type, core (InterPro:IPR003593), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Peptidase S16, Lon protease, C-terminal (InterPro:IPR001984); BEST Arabidopsis thaliana protein match is: lon protease 1 (TAIR:AT5G26860.1); Has 17176 Blast hits to 15609 proteins in 2554 species: Archae - 375; Bacteria - 9875; Metazoa - 528; Fungi - 538; Plants - 282; Viruses - 3; Other Eukaryotes - 5575 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1719958..1725268 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337610.1NP_001325548.1  lon protease 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LLK4, A0A5S9X9I7
    2. NM_111453.1NP_566259.1  lon protease 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566259.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M9L7
      UniProtKB/TrEMBL
      A0A5S9X9I7
      Conserved Domains (5) summary
      smart00464
      Location:78125
      LON; Found in ATP-dependent protease La (LON)
      TIGR00763
      Location:81938
      lon; endopeptidase La
      pfam00004
      Location:452595
      AAA; ATPase family associated with various cellular activities (AAA)
      cl21455
      Location:408475
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
      cl21678
      Location:734938
      ChlI; Subunit ChlI of Mg-chelatase