STE1 sterol 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: STE1
Official Full Name: sterol 1
Primary source: TAIR:AT3G02580
Locus tag: AT3G02580
See related: Araport:AT3G02580
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: BOULE 1; BUL1; DELTA7 STEROL C-5 DESATURASE; DWARF 7; DWF7; F16B3.21; F16B3_21; sterol 1
Summary: Brassinosteroid biosynthetic enzyme, catalyzes delta7 sterol C-5 desaturation step. Mutant has dwarf phenotype.
NEW: Try the new Gene table
Try the new Transcript table

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

both Delta(5,7)-sterol-Delta(7)-reductase and Delta(24)-sterol-Delta(24)-reductase are in addition localized to the plasma membrane, whereas Delta(7)-sterol-C(5)-desaturase was clearly detected in lipid particles
Title: Plant sterol metabolism. Δ(7)-Sterol-C5-desaturase (STE1/DWARF7), Δ(5,7)-sterol-Δ(7)-reductase (DWARF5) and Δ(24)-sterol-Δ(24)-reductase (DIMINUTO/DWARF1) show multiple subcellular localizations in Arabidopsis thaliana (Heynh) L.

Submit: New GeneRIF Correction

NM_111126.4

Function	Evidence Code	Pubs
enables C-5 sterol desaturase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables C-5 sterol desaturase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables delta7-sterol 5(6)-desaturase activity	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within brassinosteroid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within sterol biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NP_186907.1

sterol 1 (STE1); FUNCTIONS IN: C-5 sterol desaturase activity; INVOLVED IN: sterol biosynthetic process, unidimensional cell growth, brassinosteroid biosynthetic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Fatty acid hydroxylase (InterPro:IPR006694); BEST Arabidopsis thaliana protein match is: Fatty acid hydroxylase superfamily protein (TAIR:AT3G02590.1); Has 2349 Blast hits to 2348 proteins in 461 species: Archae - 0; Bacteria - 570; Metazoa - 339; Fungi - 475; Plants - 329; Viruses - 0; Other Eukaryotes - 636 (source: NCBI BLink).