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    RALF23 rapid alkalinization factor 23 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820907, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RALF23
    Official Full Name
    rapid alkalinization factor 23
    Primary source
    TAIR:AT3G16570
    Locus tag
    AT3G16570
    See related
    Araport:AT3G16570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS RAPID ALKALINIZATION FACTOR 23; ATRALF23; rapid alkalinization factor 23
    Summary
    Encodes RALF23, a member of a diversely expressed predicted peptide family showing sequence similarity to tobacco Rapid Alkalinization Factor (RALF), and is believed to play an essential role in the physiology of Arabidopsis. Consists of a single exon and is characterized by a conserved C-terminal motif and N-terminal signal peptide. RALF23 is significantly downregulated by brassinolide treatment of seedlings. Overexpression of AtRALF23 impairs brassinolide-induced hypocotyls elongation, and mature overexpressing plants are shorter and bushier. RALF23 overexpression produces slower growing seedlings with roots that have reduced capacity to acidify the rhizosphere.
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    Genomic context

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    See RALF23 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (5644593..5646557)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Protein phosphatase 2C family protein Neighboring gene threonyl and alanyl tRNA synthetase second additional domain-containing protein Neighboring gene ncRNA Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation and processing of a plant peptide hormone, AtRALF23, in Arabidopsis. Srivastava R, et al. Plant J, 2009 Sep. PMID 19473327
    2. Mechanisms of RALF peptide perception by a heterotypic receptor complex. Xiao Y, et al. Nature, 2019 Aug. PMID 31291642
    3. FERONIA Receptor Kinase Contributes to Plant Immunity by Suppressing Jasmonic Acid Signaling in Arabidopsis thaliana. Guo H, et al. Curr Biol, 2018 Oct 22. PMID 30270181
    4. Peptomics, identification of novel cationic Arabidopsis peptides with conserved sequence motifs. Olsen AN, et al. In Silico Biol, 2002. PMID 12611624
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RALF23 induces a complex between the CrRLK1L FERONIA (FER) and LORELEI (LRE)-LIKE GLYCOSYLPHOSPHATIDYLINOSITOL (GPI)-ANCHORED PROTEIN 1 (LLG1) to regulate immune signalling
      Title: Mechanisms of RALF peptide perception by a heterotypic receptor complex.
    2. The receptor kinase FERONIA (FER) functions to inhibit JA and COR signaling by phosphorylating and destabilizing MYC2, thereby positively regulating immunity. Conversely, the peptide ligand RALF23 acts through FER to stabilize MYC2 and elevate JA signaling, negatively contributing to plant immunity.
      Title: FERONIA Receptor Kinase Contributes to Plant Immunity by Suppressing Jasmonic Acid Signaling in Arabidopsis thaliana.
    3. AtRALF23 retards plant growth, and that some of BR's growth-promoting effects may be relieved by the downregulation of AtRALF23. [AtRALF23]
      Title: Regulation and processing of a plant peptide hormone, AtRALF23, in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001338245.1
    NM_001338246.1
    NM_001338247.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hormone activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in calcium-mediated signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within cell-cell signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to brassinosteroid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    rapid alkalinization factor 23
    NP_001319570.1
    • rapid alkalinization factor 23 (RALF23); CONTAINS InterPro DOMAIN/s: Rapid ALkalinization Factor (InterPro:IPR008801); BEST Arabidopsis thaliana protein match is: ralf-like 33 (TAIR:AT4G15800.1); Has 261 Blast hits to 261 proteins in 20 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 2; Plants - 259; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5644593..5646557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338245.1 → NP_001319570.1  rapid alkalinization factor 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LUS7
      UniProtKB/TrEMBL
      A0A178V8S6, A0A5S9XCQ7, A0A7G2EIT5
      Conserved Domains (1) summary
      PLN03221
      Location:1 → 137
      PLN03221; rapid alkalinization factor 23; Provisional

    2. NM_001338246.1 → NP_001327215.1  rapid alkalinization factor 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LUS7
      UniProtKB/TrEMBL
      A0A178V8S6, A0A5S9XCQ7, A0A7G2EIT5
      Conserved Domains (1) summary
      PLN03221
      Location:1 → 137
      PLN03221; rapid alkalinization factor 23; Provisional

    3. NM_001338247.1 → NP_001327214.1  rapid alkalinization factor 23 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LUS7
      UniProtKB/TrEMBL
      A0A178V8S6, A0A5S9XCQ7, A0A7G2EIT5
      Conserved Domains (1) summary
      PLN03221
      Location:1 → 137
      PLN03221; rapid alkalinization factor 23; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LUS7.1

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