FIM1 fimbrin 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: FIM1
Official Full Name: fimbrin 1
Primary source: TAIR:AT4G26700
Locus tag: AT4G26700
See related: Araport:AT4G26700
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA FIMBRIN 1; ATFIM1; F10M23.40; F10M23_40; fimbrin 1; FIMBRIN-LIKE PROTEIN
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See FIM1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 14

Sequence:: Chromosome: 4; NC_003075.7 (13463097..13467604)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

To improve fluorescence for enhanced in vivo F-actin imaging, transgenic Arabidopsis plants were generated expressing a construct with green fluorescent protein fused to both the C- and N-termini of the actin binding domain.
Title: Improved imaging of actin filaments in transgenic Arabidopsis plants expressing a green fluorescent protein fusion to the C- and N-termini of the fimbrin actin-binding domain 2.
Bound to GFP to label actin networks in multiple cell types in Nicotiana, Medicago, and Lycopersicon.
Title: A green fluorescent protein fusion to actin-binding domain 2 of Arabidopsis fimbrin highlights new features of a dynamic actin cytoskeleton in live plant cells.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

NM_001036649.1

Supported by ESTs:

NM_001036650.2

Supported by ESTs:

NM_001341828.1

Supported by ESTs:

NM_001341829.1

Supported by ESTs:

NM_118804.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in actin filament bundle assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within actin filament network formation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within circadian rhythm	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytoplasm	ISM Inferred from Sequence Model more info

General protein information

Go to the top of the page Help

Preferred Names: fimbrin 1

NP_001031726.1

fimbrin 1 (FIM1); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actinin-type, actin-binding, conserved site (InterPro:IPR001589), Calponin-homology (InterPro:IPR016146), Calponin-like actin-binding (InterPro:IPR001715); BEST Arabidopsis thaliana protein match is: Actin binding Calponin homology (CH) domain-containing protein (TAIR:AT5G55400.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_001031727.1

fimbrin 1 (FIM1); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actinin-type, actin-binding, conserved site (InterPro:IPR001589), Calponin-homology (InterPro:IPR016146), Calponin-like actin-binding (InterPro:IPR001715); BEST Arabidopsis thaliana protein match is: Actin binding Calponin homology (CH) domain-containing protein (TAIR:AT5G55400.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_194400.1

fimbrin 1 (FIM1); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actinin-type, actin-binding, conserved site (InterPro:IPR001589), Calponin-homology (InterPro:IPR016146), Calponin-like actin-binding (InterPro:IPR001715); BEST Arabidopsis thaliana protein match is: Actin binding Calponin homology (CH) domain-containing protein (TAIR:AT5G55400.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

13463097..13467604

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001341826.1 → NP_001328753.1 fimbrin 1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

O49182, O49963, Q7G188, Q9SZ12

UniProtKB/TrEMBL

A0A178V5A3
NM_001341827.1 → NP_001328754.1 fimbrin 1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V5A3, C0Z268
NM_001036649.1 → NP_001031726.1 fimbrin 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001031726.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O49182, O49963, Q7G188, Q9SZ12

UniProtKB/TrEMBL

A0A178V5A3

Conserved Domains (4) summary

smart00033
Location:398 → 496

CH; Calponin homology domain

COG5069
Location:62 → 617

SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]

pfam00307
Location:124 → 235

CH; Calponin homology (CH) domain

cl08302
Location:34 → 87

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
NM_001341828.1 → NP_001328752.1 fimbrin 1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V5A3, C0Z268
NM_001036650.2 → NP_001031727.1 fimbrin 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001031727.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V5A3, C0Z268

Conserved Domains (4) summary

smart00033
Location:398 → 496

CH; Calponin homology domain

pfam00307
Location:124 → 235

CH; Calponin homology (CH) domain

cl00030
Location:518 → 575

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cl08302
Location:34 → 87

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
NM_118804.5 → NP_194400.1 fimbrin 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_194400.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O49182, O49963, Q7G188, Q9SZ12

UniProtKB/TrEMBL

A0A178V5A3

Conserved Domains (4) summary

smart00033
Location:398 → 496

CH; Calponin homology domain

COG5069
Location:62 → 617

SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]

pfam00307
Location:124 → 235

CH; Calponin homology (CH) domain

cl08302
Location:34 → 87

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
NM_001341829.1 → NP_001328755.1 fimbrin 1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B5M7, B9DFJ1