NDB1 NAD(P)H dehydrogenase B1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: NDB1
Official Full Name: NAD(P)H dehydrogenase B1
Primary source: TAIR:AT4G28220
Locus tag: AT4G28220
See related: Araport:AT4G28220
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F26K10.100; F26K10_100; NAD(P)H dehydrogenase B1
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

The aim of this study was to define the role of external NADPH-dehydrogenase (NDB1) during oxidative metabolism of ammonium fed plants.
Title: Suppression of External NADPH Dehydrogenase-NDB1 in Arabidopsis thaliana Confers Improved Tolerance to Ammonium Toxicity via Efficient Glutathione/Redox Metabolism.
The K0.5(Ca2+) of the external NADPH dehydrogenase from Solanum tuberosum mitochondria and membranes of E. coli expressing Arabidopsis thaliana NDB1 over the physiological pH range, was determined.
Title: The Ca2+-Regulation of the Mitochondrial External NADPH Dehydrogenase in Plants Is Controlled by Cytosolic pH.
Suppression of the mitochondrial NDB1 affects central metabolism and vegetative growth.
Title: Suppression of the external mitochondrial NADPH dehydrogenase, NDB1, in Arabidopsis thaliana affects central metabolism and vegetative growth.

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NM_001341906.1

NM_118962.5

Function	Evidence Code	Pubs
enables NADH dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables NADH dehydrogenase activity	ISS Inferred from Sequence or Structural Similarity more info
enables NADPH dehydrogenase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in NADH oxidation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within NADPH oxidation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
colocalizes_with matrix side of mitochondrial inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial intermembrane space	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed

NP_567801.1

NAD(P)H dehydrogenase B1 (NDB1); FUNCTIONS IN: NADH dehydrogenase activity, disulfide oxidoreductase activity; INVOLVED IN: oxidation reduction; LOCATED IN: extrinsic to mitochondrial inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridine nucleotide-disulphide oxidoreductase, class-II (InterPro:IPR000103), FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region (InterPro:IPR001327), EF-HAND 2 (InterPro:IPR018249); BEST Arabidopsis thaliana protein match is: NAD(P)H dehydrogenase B3 (TAIR:AT4G21490.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

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