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    SEC14 Sec14p-like phosphatidylinositol transfer family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830073, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SEC14
    Official Full Name
    Sec14p-like phosphatidylinositol transfer family protein
    Primary source
    TAIR:AT4G39180
    Locus tag
    AT4G39180
    See related
    Araport:AT4G39180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA SECRETION 14; ATSEC14; SECRETION 14; T22F8.80; T22F8_80
    Summary
    encodes a protein that complements the function of a sec14(ts) mutant of S. cerevisiae
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    Genomic context

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    See SEC14 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    16
    Sequence:
    Chromosome: 4; NC_003075.7 (18243726..18248805, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Homeodomain-like superfamily protein Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nucleolar-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sec14-nodulin proteins and the patterning of phosphoinositide landmarks for developmental control of membrane morphogenesis. Ghosh R, et al. Mol Biol Cell, 2015 May 1. PMID 25739452, Free PMC Article
    2. Isolation of a cDNA from Arabidopsis thaliana that complements the sec14 mutant of yeast. Jouannic N, et al. Eur J Biochem, 1998 Dec 1. PMID 9874205
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001342526.1
    NM_120078.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidylinositol transfer activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphatidylcholine biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within phospholipid transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Sec14p-like phosphatidylinositol transfer family protein
    NP_001190963.1
    • SECRETION 14 (SEC14); FUNCTIONS IN: phosphatidylinositol transporter activity; INVOLVED IN: phosphatidylcholine biosynthetic process; LOCATED IN: intracellular; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Cellular retinaldehyde-binding/triple function, C-terminal (InterPro:IPR001251), Cellular retinaldehyde-binding/triple function, N-terminal (InterPro:IPR008273), Cellular retinaldehyde binding/alpha-tocopherol transport (InterPro:IPR001071), Phosphatidylinositol transfer protein-like, N-terminal (InterPro:IPR011074); BEST Arabidopsis thaliana protein match is: SEC14-like 3 (TAIR:AT2G21540.2).
    NP_195629.2
    • SECRETION 14 (SEC14); FUNCTIONS IN: phosphatidylinositol transporter activity; INVOLVED IN: phosphatidylcholine biosynthetic process; LOCATED IN: intracellular; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Cellular retinaldehyde-binding/triple function, C-terminal (InterPro:IPR001251), Cellular retinaldehyde-binding/triple function, N-terminal (InterPro:IPR008273), Cellular retinaldehyde binding/alpha-tocopherol transport (InterPro:IPR001071), Phosphatidylinositol transfer protein-like, N-terminal (InterPro:IPR011074); BEST Arabidopsis thaliana protein match is: SEC14-like 3 (TAIR:AT2G21540.3); Has 2899 Blast hits to 2883 proteins in 237 species: Archae - 0; Bacteria - 0; Metazoa - 924; Fungi - 653; Plants - 892; Viruses - 0; Other Eukaryotes - 430 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      18243726..18248805 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001204034.2 → NP_001190963.1  Sec14p-like phosphatidylinositol transfer family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190963.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V7D6, F4JVA8
      Conserved Domains (3) summary
      smart00516
      Location:138 → 308
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
      smart01100
      Location:72 → 115
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      cl09111
      Location:490 → 528
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    2. NM_120078.2 → NP_195629.2  Sec14p-like phosphatidylinositol transfer family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195629.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JVA9, Q9T027
      UniProtKB/TrEMBL
      A0A178V5C6
      Conserved Domains (3) summary
      smart00516
      Location:138 → 308
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
      smart01100
      Location:72 → 115
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      cl09111
      Location:491 → 529
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    3. NM_001342526.1 → NP_001329546.1  Sec14p-like phosphatidylinositol transfer family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V7D6, F4JVA8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JVA9.1

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