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    Ubiquitin carboxyl-terminal hydrolase-related protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823946, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Ubiquitin carboxyl-terminal hydrolase-related protein
    Primary source
    TAIR:AT3G47910
    Locus tag
    AT3G47910
    See related
    Araport:AT3G47910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    15
    Sequence:
    Chromosome: 3; NC_003074.8 (17674287..17681730, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Ubiquitin carboxyl-terminal hydrolase-related protein Neighboring gene Ta11-like non-LTR retrotransposon Neighboring gene L-galactono-1,4-lactone dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001125316.2
    NM_114660.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquitin carboxyl-terminal hydrolase-related protein
    NP_001118788.1
    • Ubiquitin carboxyl-terminal hydrolase-related protein; FUNCTIONS IN: ubiquitin thiolesterase activity, zinc ion binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: intracellular; EXPRESSED IN: cultured cell; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF627 (InterPro:IPR006866), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394), Zinc finger, C2H2-type (InterPro:IPR007087), Protein of unknown function DUF629 (InterPro:IPR006865); BEST Arabidopsis thaliana protein match is: Ubiquitin carboxyl-terminal hydrolase-related protein (TAIR:AT3G47890.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_190374.4
    • Ubiquitin carboxyl-terminal hydrolase-related protein; FUNCTIONS IN: ubiquitin thiolesterase activity, zinc ion binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: intracellular; EXPRESSED IN: cultured cell; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF627 (InterPro:IPR006866), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394), Zinc finger, C2H2-type (InterPro:IPR007087), Protein of unknown function DUF629 (InterPro:IPR006865); BEST Arabidopsis thaliana protein match is: Ubiquitin carboxyl-terminal hydrolase-related protein (TAIR:AT3G47890.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17674287..17681730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001125316.2 → NP_001118788.1  Ubiquitin carboxyl-terminal hydrolase-related protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118788.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VDH0, A0A5S9XJ23, F4JCR3
      Conserved Domains (4) summary
      sd00006
      Location:60 → 84
      TPR; TPR repeat [structural motif]
      pfam00443
      Location:1275 → 1604
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam04780
      Location:329 → 852
      DUF629; Protein of unknown function (DUF629)
      pfam04781
      Location:62 → 171
      DUF627; Protein of unknown function (DUF627)

    2. NM_114660.5 → NP_190374.4  Ubiquitin carboxyl-terminal hydrolase-related protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190374.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VF36, F4JCR2
      Conserved Domains (7) summary
      cd02257
      Location:1365 → 1604
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      cl02553
      Location:1285 → 1436
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      sd00006
      Location:60 → 84
      TPR; TPR repeat [structural motif]
      pfam00443
      Location:1274 → 1603
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam04780
      Location:329 → 852
      DUF629; Protein of unknown function (DUF629)
      pfam04781
      Location:62 → 171
      DUF627; Protein of unknown function (DUF627)
      pfam13414
      Location:104 → 170
      TPR_11; TPR repeat
    Nucleotide Protein
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