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    TT7 Cytochrome P450 superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830693, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TT7
    Official Full Name
    Cytochrome P450 superfamily protein
    Primary source
    TAIR:AT5G07990
    Locus tag
    AT5G07990
    See related
    Araport:AT5G07990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CYP75B1; CYTOCHROME P450 75B1; D501; F13G24.190; F13G24_190; F3'H; FLAVONOID 3'-HYDROXYLASE; TRANSPARENT TESTA 7
    Summary
    Required for flavonoid 3' hydroxylase activity. Enzyme abundance relative to CHS determines Quercetin/Kaempferol metabolite ratio.
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    Genomic context

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    See TT7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (2560328..2563137)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene dentin sialophosphoprotein-like protein Neighboring gene dentin sialophosphoprotein-like protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glucan endo-1,3-beta-glucosidase-like protein 3 Neighboring gene flavonoid protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the Arabidopsis thaliana flavonoid 3'-hydroxylase gene and functional expression of the encoded P450 enzyme. Schoenbohm C, et al. Biol Chem, 2000 Aug. PMID 11030432
    2. Flavonols modulate lateral root emergence by scavenging reactive oxygen species in Arabidopsis thaliana. Chapman JM, et al. J Biol Chem, 2021 Jan-Jun. PMID 33839683, Free PMC Article
    3. Auxin and ethylene induce flavonol accumulation through distinct transcriptional networks. Lewis DR, et al. Plant Physiol, 2011 May. PMID 21427279, Free PMC Article
    4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Flavonols modulate lateral root emergence by scavenging reactive oxygen species in Arabidopsis thaliana.
      Title: Flavonols modulate lateral root emergence by scavenging reactive oxygen species in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120881.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables flavonoid 3'-monooxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables flavonoid 3'-monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavonoid 3'-monooxygenase activity TAS
    Traceable Author Statement
    more info
    		  
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in flavonoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within flavonoid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to UV IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Cytochrome P450 superfamily protein
    NP_196416.1
    • TRANSPARENT TESTA 7 (TT7); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 706, subfamily A, polypeptide 6 (TAIR:AT4G12320.1); Has 35179 Blast hits to 34934 proteins in 1774 species: Archae - 51; Bacteria - 4733; Metazoa - 12156; Fungi - 7299; Plants - 9637; Viruses - 3; Other Eukaryotes - 1300 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2560328..2563137
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120881.3 → NP_196416.1  Cytochrome P450 superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196416.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SD85
      UniProtKB/TrEMBL
      A0A178UNZ9, A0A5S9Y2Q7
      Conserved Domains (1) summary
      PLN02687
      Location:2 → 511
      PLN02687; flavonoid 3'-monooxygenase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SD85.1

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