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    EMB2024 NagB/RpiA/CoA transferase-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832511, updated on 18-Sep-2024

    Summary

    Official Symbol
    EMB2024
    Official Full Name
    NagB/RpiA/CoA transferase-like superfamily protein
    Primary source
    TAIR:AT5G24400
    Locus tag
    AT5G24400
    See related
    Araport:AT5G24400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    6-PHOSPHOGLUCONOLACTONASE 3; EMBRYO DEFECTIVE 2024; K16H17.11; K16H17_11; PGL3
    Summary
    Encodes a protein with 6-phosphoglucunolactonase activity that localizes to the chloroplasts and the peroxisome. However, mutant phenotypes observed in pgl3 mutant plants can be complemented with a chloroplast-targeted version of the protein. PGL3 likely functions in the oxidative branch of the pentose phosphate pathway. pgl3 mutant phenotypes suggest that it is important in pathogen defense and maintenance of cellular redox homeostasis.
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    Genomic context

    See EMB2024 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (8330243..8331963, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily protein Neighboring gene YELLOW STRIPE like 2 Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene 6-phosphogluconolactonase 4 Neighboring gene 6-phosphogluconolactonase 5

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    NM_122348.3

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in chloroplast PubMed 
    located_in chloroplast PubMed 
    located_in chloroplast  
    located_in chloroplast stroma PubMed 
    NOT located_in cytosol PubMed 
    located_in peroxisome PubMed 
    located_in peroxisome PubMed 
    located_in plastid PubMed 

    General protein information

    Preferred Names
    NagB/RpiA/CoA transferase-like superfamily protein
    NP_568445.1
    • EMBRYO DEFECTIVE 2024 (EMB2024); FUNCTIONS IN: 6-phosphogluconolactonase activity, catalytic activity; INVOLVED IN: defense response to oomycetes, defense response to bacterium, carbohydrate metabolic process, cellular response to redox state, embryo development ending in seed dormancy; LOCATED IN: peroxisome, chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glucosamine/galactosamine-6-phosphate isomerase (InterPro:IPR006148), 6-phosphogluconolactonase, DevB-type (InterPro:IPR005900); BEST Arabidopsis thaliana protein match is: 6-phosphogluconolactonase 2 (TAIR:AT3G49360.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8330243..8331963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122348.3 → NP_568445.1  NagB/RpiA/CoA transferase-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568445.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42135, Q84WW2, Q8LD77, Q9FIN2
      UniProtKB/TrEMBL
      A0A5S9Y978, A0A654G497
      Conserved Domains (1) summary
      cl00339
      Location:78 → 325
      SugarP_isomerase; Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose ...
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