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    GAUT12 galacturonosyltransferase 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835558, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GAUT12
    Official Full Name
    galacturonosyltransferase 12
    Primary source
    TAIR:AT5G54690
    Locus tag
    AT5G54690
    See related
    Araport:AT5G54690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    galacturonosyltransferase 12; IRREGULAR XYLEM 8; IRX8; K5F14.3; K5F14_3; LGT6
    Summary
    Encodes a protein with putative galacturonosyltransferase activity. Mutants defective in this gene displayed a notable reduction in xylose (>50%) in the cell walls from stems and roots and a reduction in cellulose (~25%).
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    Genomic context

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    See GAUT12 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (22219224..22221968, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene kinesin 3 Neighboring gene ncRNA Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene Ankyrin repeat family protein Neighboring gene Ankyrin repeat family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of PoGT8D and PoGT43B, two secondary wall-associated glycosyltransferases in poplar. Zhou GK, et al. Plant Cell Physiol, 2007 May. PMID 17379696
    2. Arabidopsis irregular xylem8 and irregular xylem9: implications for the complexity of glucuronoxylan biosynthesis. Peña MJ, et al. Plant Cell, 2007 Feb. PMID 17322407, Free PMC Article
    3. The Arabidopsis irregular xylem8 mutant is deficient in glucuronoxylan and homogalacturonan, which are essential for secondary cell wall integrity. Persson S, et al. Plant Cell, 2007 Jan. PMID 17237350, Free PMC Article
    4. Functional identification of an Arabidopsis pectin biosynthetic homogalacturonan galacturonosyltransferase. Sterling JD, et al. Proc Natl Acad Sci U S A, 2006 Mar 28. PMID 16540543, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_124850.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables polygalacturonate 4-alpha-galacturonosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glucuronoxylan biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glucuronoxylan metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pectin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within xylan biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    galacturonosyltransferase 12
    NP_200280.1
    • galacturonosyltransferase 12 (GAUT12); CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 8 (InterPro:IPR002495); BEST Arabidopsis thaliana protein match is: galacturonosyltransferase 13 (TAIR:AT3G01040.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22219224..22221968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124850.4 → NP_200280.1  galacturonosyltransferase 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200280.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FH36
      UniProtKB/TrEMBL
      A0A5S9YE23, A0A654GBH9, W8QN47
      Conserved Domains (1) summary
      PLN02659
      Location:1 → 535
      PLN02659; Probable galacturonosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FH36.1

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