CKX1 cytokinin oxidase/dehydrogenase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: CKX1
Official Full Name: cytokinin oxidase/dehydrogenase 1
Primary source: TAIR:AT2G41510
Locus tag: AT2G41510
See related: Araport:AT2G41510
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATCKX1; cytokinin oxidase/dehydrogenase 1; CYTOKININ OXIDASE/DEHYDROGENASE 1; T32G6.3; T32G6_3
Summary: It encodes a protein whose sequence is similar to cytokinin oxidase/dehydrogenase, which catalyzes the degradation of cytokinins.
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

oligomerization is a crucial parameter regulating CKX1 biological activity and the cytokinin concentration in the endoplasmic reticulum.
Title: The Cytokinin Oxidase/Dehydrogenase CKX1 Is a Membrane-Bound Protein Requiring Homooligomerization in the Endoplasmic Reticulum for Its Cellular Activity.

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NM_001336920.1

Function	Evidence Code	Pubs
enables FAD binding	IEA Inferred from Electronic Annotation more info
enables cytokinin dehydrogenase activity	IDA Inferred from Direct Assay more info	PubMed
enables cytokinin dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables cytokinin dehydrogenase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cytokinin catabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within cytokinin catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cytokinin metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within meristem development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in vacuole	IDA Inferred from Direct Assay more info	PubMed

NP_001318403.1

cytokinin oxidase/dehydrogenase 1 (CKX1); FUNCTIONS IN: cytokinin dehydrogenase activity; INVOLVED IN: N-terminal protein myristoylation, cytokinin catabolic process, meristem development; LOCATED IN: vacuole; EXPRESSED IN: lateral root, shoot apex, hypocotyl, root, flower; CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), Oxygen oxidoreductase covalent FAD-binding site (InterPro:IPR006093), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase/dehydrogenase 6 (TAIR:AT3G63440.1); Has 6769 Blast hits to 6763 proteins in 1376 species: Archae - 168; Bacteria - 3882; Metazoa - 142; Fungi - 1302; Plants - 645; Viruses - 0; Other Eukaryotes - 630 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain