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    LINC02245 long intergenic non-protein coding RNA 2245 [ Homo sapiens (human) ]

    Gene ID: 400958, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC02245provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2245provided by HGNC
    Primary source
    HGNC:HGNC:53134
    See related
    AllianceGenome:HGNC:53134
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC02245 in Genome Data Viewer
    Location:
    2p14
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (64901840..64932447, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (64911457..64942061, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (65128974..65159581, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 341, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:65058033-65059232 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:65065480-65066679 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15909 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15910 Neighboring gene long intergenic non-protein coding RNA 1800 Neighboring gene Sharpr-MPRA regulatory region 2197 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65087040-65087243 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15911 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11569 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65103167-65103373 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65131242-65131436 Neighboring gene Sharpr-MPRA regulatory region 15627 Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15912 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15913 Neighboring gene RNA, 7SL, cytoplasmic 211, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15914 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15915 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15916 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15917 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15918 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15919 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:65165275-65165830 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15920 Neighboring gene ribosomal protein L11 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15921 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15922 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11570 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:65216535-65217119 Neighboring gene RNA, U6 small nuclear 548, pseudogene Neighboring gene solute carrier family 1 member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. lncRNAs as Novel Indicators of Patients' Prognosis in Stage I Epithelial Ovarian Cancer: A Retrospective and Multicentric Study. Martini P, et al. Clin Cancer Res, 2017 May 1. PMID 27827314
    2. Long Noncoding RNA SERTAD2-3 Inhibits Osteosarcoma Proliferation and Migration by Competitively Binding miR-29c. Zhang Z, et al. Genet Test Mol Biomarkers, 2020 Feb. PMID 31999493
    3. Super-lncRNAs: identification of lncRNAs that target super-enhancers via RNA:DNA:DNA triplex formation. Soibam B. RNA, 2017 Nov. PMID 28839111, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Long Noncoding RNA SERTAD2-3 Inhibits Osteosarcoma Proliferation and Migration by Competitively Binding miR-29c.
      Title: Long Noncoding RNA SERTAD2-3 Inhibits Osteosarcoma Proliferation and Migration by Competitively Binding miR-29c.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • lnc-SERTAD2-3

    Clone Names

    • AC007386.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_036586.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007386, BC037562

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      64901840..64932447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      64911457..64942061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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