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    LINC01291 long intergenic non-protein coding RNA 1291 [ Homo sapiens (human) ]

    Gene ID: 102724515, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC01291provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1291provided by HGNC
    Primary source
    HGNC:HGNC:50358
    See related
    Ensembl:ENSG00000204792 AllianceGenome:HGNC:50358
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LINC01293
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC01291 in Genome Data Viewer
    Location:
    2p12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (74908961..74943494)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (74917835..74952367)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (75136088..75170621)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11673 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11674 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:75061972-75062848 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:75064008-75064523 Neighboring gene Sharpr-MPRA regulatory region 11570 Neighboring gene HK2 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16083 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:75082772-75083312 Neighboring gene hexokinase 2 Neighboring gene uncharacterized LOC105374809 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:75185356-75185856 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:75185857-75186357 Neighboring gene DNA polymerase epsilon 4, accessory subunit Neighboring gene NANOG hESC enhancer GRCh37_chr2:75211079-75211580 Neighboring gene uncharacterized LOC124907850

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. LINC01291 promotes hepatocellular carcinoma development by targeting the miR-186-5p/OXSR1 axis. Chu J, et al. J Gene Med, 2022 Feb. PMID 34665488
    2. Long noncoding RNA LINC01291 promotes the aggressive properties of melanoma by functioning as a competing endogenous RNA for microRNA-625-5p and subsequently increasing IGF-1R expression. Wu L, et al. Cancer Gene Ther, 2022 Mar. PMID 33674778, Free PMC Article
    3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. Dias Neto E, et al. Proc Natl Acad Sci U S A, 2000 Mar 28. PMID 10737800, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC01291 promotes hepatocellular carcinoma development by targeting the miR-186-5p/OXSR1 axis.
      Title: LINC01291 promotes hepatocellular carcinoma development by targeting the miR-186-5p/OXSR1 axis.
    2. Long noncoding RNA LINC01291 promotes the aggressive properties of melanoma by functioning as a competing endogenous RNA for microRNA-625-5p and subsequently increasing IGF-1R expression.
      Title: Long noncoding RNA LINC01291 promotes the aggressive properties of melanoma by functioning as a competing endogenous RNA for microRNA-625-5p and subsequently increasing IGF-1R expression.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • TCONS_00002938
    • long intergenic non-protein coding RNA 1293

    Clone Names

    • FLJ43972, AC104135.3, AC104135.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_125792.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC104135

    2. NR_189601.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC104135

    3. NR_189602.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC104135
      Related
      ENST00000717897.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      74908961..74943494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      74917835..74952367
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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