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    FOXD4L4 forkhead box D4 like 4 [ Homo sapiens (human) ]

    Gene ID: 349334, updated on 10-Dec-2024

    Summary

    Official Symbol
    FOXD4L4provided by HGNC
    Official Full Name
    forkhead box D4 like 4provided by HGNC
    Primary source
    HGNC:HGNC:23762
    See related
    Ensembl:ENSG00000184659 MIM:611085; AllianceGenome:HGNC:23762
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FOXD4b; FOXD4L2; bA460E7.2
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See FOXD4L4 in Genome Data Viewer
    Location:
    9q21.11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (65737146..65738396)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (80057244..80058494, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (70427649..70428899, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene FSHD region gene 1 family member K, pseudogene Neighboring gene Zn regulated GTPase metalloprotein activator 1E Neighboring gene Sharpr-MPRA regulatory region 13873 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:70489243-70489833 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:70450935-70451544 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:70427620-70428156 Neighboring gene immunoglobulin kappa variable 1/OR-3 (pseudogene) Neighboring gene uncharacterized LOC101928381

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    forkhead box protein D4-like 4
    Names
    FOXD4-like 4
    forkhead box D4-like 2
    forkhead box protein D4-like 2
    forkhead box protein D4b
    myeloid factor-gamma
    winged helix factor-1
    winged helix transcription factor beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199244.3NP_954714.2  forkhead box protein D4-like 4

      See identical proteins and their annotated locations for NP_954714.2

      Status: INFERRED

      Source sequence(s)
      BX284632
      Consensus CDS
      CCDS75845.1
      UniProtKB/Swiss-Prot
      Q5RIB4, Q6VB85, Q8WXT5
      UniProtKB/TrEMBL
      Q3MI95
      Related
      ENSP00000366630.1, ENST00000377413.3
      Conserved Domains (1) summary
      pfam00250
      Location:108194
      Forkhead; Forkhead domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      65737146..65738396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      80057244..80058494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001099279.1: Suppressed sequence

      Description
      NM_001099279.1: This RefSeq was permanently suppressed because it is a redundant RefSeq for this FOXD4-like family member.