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    AGRN agrin [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700400, updated on 17-Aug-2024

    Summary

    Official Symbol
    AGRNprovided by VGNC
    Official Full Name
    agrinprovided by VGNC
    Primary source
    VGNC:VGNC:69749
    See related
    Ensembl:ENSMMUG00000000838
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See AGRN in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (223364496..223400890, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (120979..156677)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene ring finger protein 223 Neighboring gene uncharacterized LOC114674603 Neighboring gene ISG15 ubiquitin like modifier Neighboring gene midkine pseudogene Neighboring gene hes family bHLH transcription factor 4

    Genomic regions, transcripts, and products

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      223364496..223400890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028841630.1XP_028697463.1  agrin isoform X6

      UniProtKB/TrEMBL
      H9FU63
      Conserved Domains (10) summary
      smart00280
      Location:481526
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:10571181
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:17521784
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:348388
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:13041453
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03146
      Location:43145
      NtA; Agrin NtA domain
      pfam00008
      Location:12601292
      EGF; EGF-like domain
      pfam00053
      Location:720767
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:18481978
      Laminin_G_1; Laminin G domain
      cl00097
      Location:276316
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    2. XM_028841629.1XP_028697462.1  agrin isoform X5

      UniProtKB/TrEMBL
      H9FU64
      Conserved Domains (10) summary
      smart00280
      Location:553598
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:11291253
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:18201852
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:420460
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:13761525
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03146
      Location:43145
      NtA; Agrin NtA domain
      pfam00008
      Location:13321364
      EGF; EGF-like domain
      pfam00053
      Location:792839
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:18972027
      Laminin_G_1; Laminin G domain
      cl00097
      Location:348388
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    3. XM_028841623.1XP_028697456.1  agrin isoform X2

      UniProtKB/TrEMBL
      H9FU64
      Conserved Domains (10) summary
      smart00280
      Location:553598
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:11291253
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:18201852
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:420460
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:13761525
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03146
      Location:43145
      NtA; Agrin NtA domain
      pfam00008
      Location:13321364
      EGF; EGF-like domain
      pfam00053
      Location:792839
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:19162046
      Laminin_G_1; Laminin G domain
      cl00097
      Location:348388
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    4. XM_028841628.1XP_028697461.1  agrin isoform X4

      UniProtKB/TrEMBL
      H9FU63
      Related
      ENSMMUP00000040699.3, ENSMMUT00000047676.3
      Conserved Domains (10) summary
      smart00280
      Location:553598
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:11291253
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:18241856
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:420460
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:13761525
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03146
      Location:43145
      NtA; Agrin NtA domain
      pfam00008
      Location:13321364
      EGF; EGF-like domain
      pfam00053
      Location:792839
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:19012031
      Laminin_G_1; Laminin G domain
      cl00097
      Location:348388
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    5. XM_028841627.1XP_028697460.1  agrin isoform X3

      UniProtKB/TrEMBL
      H9FU63
      Related
      ENSMMUP00000069066.1, ENSMMUT00000082247.1
      Conserved Domains (10) summary
      smart00280
      Location:553598
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:11291253
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:18241856
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:420460
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:13761525
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03146
      Location:43145
      NtA; Agrin NtA domain
      pfam00008
      Location:13321364
      EGF; EGF-like domain
      pfam00053
      Location:792839
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:19092039
      Laminin_G_1; Laminin G domain
      cl00097
      Location:348388
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    6. XM_015110472.2XP_014965958.2  agrin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QLN8, H9FU63
      Related
      ENSMMUP00000048963.2, ENSMMUT00000060320.2
      Conserved Domains (10) summary
      smart00280
      Location:553598
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:11291253
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:18241856
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:420460
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:13761525
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03146
      Location:43145
      NtA; Agrin NtA domain
      pfam00008
      Location:13321364
      EGF; EGF-like domain
      pfam00053
      Location:792839
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:19202050
      Laminin_G_1; Laminin G domain
      cl00097
      Location:348388
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    7. XM_028841643.1XP_028697476.1  agrin isoform X9

      UniProtKB/TrEMBL
      A0A1D5QUS1
      Related
      ENSMMUP00000051801.2, ENSMMUT00000053248.2
      Conserved Domains (9) summary
      smart00280
      Location:380425
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:9561080
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:16511683
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:247287
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:12031352
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:11591191
      EGF; EGF-like domain
      pfam00053
      Location:619666
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:17471877
      Laminin_G_1; Laminin G domain
      cl00097
      Location:175215
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    8. XM_028841634.1XP_028697467.1  agrin isoform X7

      UniProtKB/TrEMBL
      A0A1D5QUS1, A0A5F7ZUP2
      Related
      ENSMMUP00000068878.1, ENSMMUT00000097734.1
      Conserved Domains (9) summary
      smart00280
      Location:449494
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:10251149
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:17201752
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:316356
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:12721421
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:12281260
      EGF; EGF-like domain
      pfam00053
      Location:688735
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:18161946
      Laminin_G_1; Laminin G domain
      cl00097
      Location:244284
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    9. XM_028841648.1XP_028697481.1  agrin isoform X10

      UniProtKB/TrEMBL
      A0A1D5QUS1
      Conserved Domains (9) summary
      smart00280
      Location:377422
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:9531077
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:16481680
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:244284
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:12001349
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:11561188
      EGF; EGF-like domain
      pfam00053
      Location:616663
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:17441874
      Laminin_G_1; Laminin G domain
      cl00097
      Location:172212
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    10. XM_028841640.1XP_028697473.1  agrin isoform X8

      UniProtKB/TrEMBL
      H9FU63
      Conserved Domains (9) summary
      smart00280
      Location:449494
      KAZAL; Kazal type serine protease inhibitors
      smart00200
      Location:10251149
      SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
      cd00054
      Location:17201752
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00104
      Location:316356
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
      cd00110
      Location:12721421
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:12281260
      EGF; EGF-like domain
      pfam00053
      Location:688735
      Laminin_EGF; Laminin EGF domain
      pfam00054
      Location:17971927
      Laminin_G_1; Laminin G domain
      cl00097
      Location:244284
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...