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    CDK5RAP2 CDK5 regulatory subunit associated protein 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701442, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CDK5RAP2provided by VGNC
    Official Full Name
    CDK5 regulatory subunit associated protein 2provided by VGNC
    Primary source
    VGNC:VGNC:71014
    See related
    Ensembl:ENSMMUG00000023255
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CDK5RAP2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (22135059..22325680)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (18698761..18892236)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672733 Neighboring gene adenosylhomocysteinase-like Neighboring gene multiple EGF like domains 9 Neighboring gene uncharacterized LOC114672734 Neighboring gene uncharacterized LOC106993621 Neighboring gene microRNA mir-147a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables gamma-tubulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in centriole replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of mitotic spindle orientation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in microtubule bundle formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of centriole replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of microtubule polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mitotic cell cycle spindle assembly checkpoint IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microtubule plus-end IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitotic spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in pericentriolar material IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CDK5 regulatory subunit-associated protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      22135059..22325680
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028834907.1 → XP_028690740.1  CDK5 regulatory subunit-associated protein 2 isoform X6

      UniProtKB/TrEMBL
      G7NG25
      Conserved Domains (3) summary
      COG1196
      Location:137 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07989
      Location:61 → 129
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:965 → 1069
      NUT; NUT protein

    2. XM_028834909.1 → XP_028690742.1  CDK5 regulatory subunit-associated protein 2 isoform X8

      UniProtKB/TrEMBL
      F7DIF0
      Conserved Domains (3) summary
      COG1196
      Location:137 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07989
      Location:61 → 129
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:735 → 839
      NUT; NUT protein

    3. XM_015116954.2 → XP_014972440.2  CDK5 regulatory subunit-associated protein 2 isoform X1

      UniProtKB/TrEMBL
      G7NG25
      Related
      ENSMMUP00000030614.4, ENSMMUT00000032716.4
      Conserved Domains (3) summary
      COG1196
      Location:137 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07989
      Location:61 → 129
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:965 → 1069
      NUT; NUT protein

    4. XM_028834905.1 → XP_028690738.1  CDK5 regulatory subunit-associated protein 2 isoform X4

      UniProtKB/TrEMBL
      F7HTZ4
      Related
      ENSMMUP00000039799.3, ENSMMUT00000046771.3
      Conserved Domains (3) summary
      COG1196
      Location:137 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07989
      Location:61 → 129
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:965 → 1069
      NUT; NUT protein

    5. XM_015116957.2 → XP_014972443.2  CDK5 regulatory subunit-associated protein 2 isoform X3

      UniProtKB/TrEMBL
      F7DIG6, G7NG25
      Related
      ENSMMUP00000030615.4, ENSMMUT00000032717.4
      Conserved Domains (4) summary
      COG1196
      Location:137 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02169
      Location:391 → 681
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam07989
      Location:61 → 129
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:933 → 1037
      NUT; NUT protein

    6. XM_028834908.1 → XP_028690741.1  CDK5 regulatory subunit-associated protein 2 isoform X7

      UniProtKB/TrEMBL
      F7DIF0
      Related
      ENSMMUP00000030617.4, ENSMMUT00000032719.4
      Conserved Domains (3) summary
      COG1196
      Location:137 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07989
      Location:61 → 129
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:736 → 840
      NUT; NUT protein

    7. XM_015116955.2 → XP_014972441.2  CDK5 regulatory subunit-associated protein 2 isoform X2

      UniProtKB/TrEMBL
      G7NG25
      Conserved Domains (3) summary
      COG1196
      Location:137 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07989
      Location:61 → 129
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:964 → 1068
      NUT; NUT protein

    8. XM_028834906.1 → XP_028690739.1  CDK5 regulatory subunit-associated protein 2 isoform X5

      UniProtKB/TrEMBL
      G7NG25
      Conserved Domains (3) summary
      COG1196
      Location:78 → 438
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07989
      Location:2 → 70
      Cnn_1N; Centrosomin N-terminal motif 1
      pfam12881
      Location:906 → 1010
      NUT; NUT protein

    9. XM_028834910.1 → XP_028690743.1  CDK5 regulatory subunit-associated protein 2 isoform X9

      UniProtKB/TrEMBL
      G7NG25
      Conserved Domains (2) summary
      COG1196
      Location:2 → 343
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam12881
      Location:687 → 791
      NUT; NUT protein
    Nucleotide Protein
    Heading Accession and Version

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